SynthesisJournal of hepato-biliary-pancreatic sciences2026
Open Versus Laparoscopic and Robotic Approach in Hilar Cholangiocarcinoma: A Network Meta-Analysis With Trial Sequential Analysis.
Synthesis in Journal of hepato-biliary-pancreatic sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- From scalpel to console: a bibliometric and knowledge-mapping analysis of robot-assisted cholangiocarcinoma surgery.Journal of robotic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of minimally invasive (MI) techniques for Hilar cholangiocarcinoma (HCCA) has increased in the last years, but high-quality evidence remains limited. This study aims to assess the safety of laparoscopic (LPS) and robotic (ROB) approaches compared to open surgery in the treatment of HCCA.
methodsAfter a systematic search, a frequentist network meta-analysis and a Trial sequential analysis were performed. Primary outcomes set for the study were major complications and R0 rate.
resultsFourteen studies including 1169 patients were found eligible, of which 403 were LPS (34.5%) and 137 operated with a ROB approach (11.7%). ROB and LPS techniques showed statistically similar rates of major complications (p = 0.251 and p = 0.143), while ROB was associated with a higher rate of negative resection margins (OR: 2.856, 95% CI: 1.585-5.144; p < 0.001). No differences were observed in the secondary outcomes assessed, except for the operative time, higher in both MI approaches, and length of stay, shorter in the ROB group.
conclusionsGlobal experience in MI surgery for HCCA remains limited and subject to potential bias. Nevertheless, both LPS and ROB approaches seem to represent safe and viable options for carefully selected patients when performed by experienced surgeons in high-volume centers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.