Evidence map›Paper›PMID 42067969›Full record

ArticlePest management science2026

Target-gene overexpression and metabolic enhancement confer bentazone resistance in Amaranthus retroflexus.

Chang Liu, Shen Wang, Di Ma, Xuelian Liu, Xiaofeng Xu, Wenpeng Sun, Chunjie Li, Zhonghua Sun, Chunhong Teng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Chang Liu *College of Plant Protection, Northeast Agricultural University, Harbin, China.
Shen Wang *College of Plant Protection, Northeast Agricultural University, Harbin, China.
Di MaCollege of Plant Protection, Northeast Agricultural University, Harbin, China.
Xuelian LiuCollege of Plant Protection, Northeast Agricultural University, Harbin, China.
Xiaofeng XuCollege of Plant Protection, Northeast Agricultural University, Harbin, China.
Wenpeng SunCollege of Agriculture, Northeast Agricultural University, Harbin, China.
Chunjie LiState Key Laboratory of Black Soils Conservation and Utilization, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Harbin, China.
Zhonghua SunCollege of Plant Protection, Northeast Agricultural University, Harbin, China.ORCID https://orcid.org/0000-0001-9642-3857
Chunhong TengCollege of Plant Protection, Northeast Agricultural University, Harbin, China.

Funding

China Agriculture Research System of MOF and MARA (CARS-04)Natural Science Foundation of Heilongjiang Province (LH2024C009)"Young Talents" Project of Northeast Agricultural University (22QC04 and 21QC02)
6 · The paper itself

Abstract

backgroundResistance to photosystem II (PSII)-inhibiting herbicides is increasingly widespread in Amaranthus retroflexus, a major weed in soybean production, yet the underlying mechanisms remain unclear. This study aimed to characterize the molecular basis of bentazone (BTZ) resistance in this species.

resultsBTZ-resistant genotype (B24) showed a resistance index of 11.30 relative to susceptible B06. No target-site mutations were found, but psbA expression was 1.14-to 2.42-fold higher in B24. Transcriptomics and RT-qPCR identified 11 significantly upregulated genes, including four glycosyltransferases, three ABC transporters, and four cytochrome P450s. Molecular docking revealed strong binding of BTZ with ArUGT86A2, ArABCG5, and ArCYP71A1, and heterologous expression in yeast confirmed that ArCYP71A1 confers BTZ resistance.

conclusionThis research provides the first evidence that both target-site overexpression and metabolic enhancement drive BTZ resistance in A. retroflexus. These findings establish a foundation for mechanistic studies and improved management of resistant populations. © 2026 Society of Chemical Industry.

Indexed as

AmaranthusBenzothiadiazinesHerbicide ResistanceHerbicidesMolecular Docking SimulationbentazoneBenzothiadiazinesHerbicidesAmaranthus retroflexusArCYP71A1bentazonemetabolic resistance

Identifiers

PMID42067969
PMCPMC13352408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.