Evidence map›Paper›PMID 42067848›Full record

ArticleBMC musculoskeletal disorders2026

Value of CT in quantitatively diagnosing and assessing collapse in patients with femoral head necrosis based on finite element mechanics analysis.

Tong Yu, Limin Xie, Zhihai Zhang, Shan Shi, Wenjuan Tan, Zhixiu Hao, You Zhou, Xin Li, Zhennan Zhang

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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Tong YuDepartment of Orthopedics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Limin XieDepartment of Orthopedics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Zhihai ZhangDepartment of Orthopedics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Shan ShiDepartment of Radiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Wenjuan TanSchool of Mechanical Engineering, Tsinghua University, Beijing, 100084, China.
Zhixiu HaoSchool of Mechanical Engineering, Tsinghua University, Beijing, 100084, China.
You ZhouDepartment of Orthopedics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Xin LiDepartment of Orthopedics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Zhennan ZhangMedical Services Section, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China. zhangnan2009_cool@126.com.

Funding

High-Level Chinese Medical Hospital Promotion Project HLCMHPP20230121National Natural Science Foundation of China 82405148Research Fund Project of Guang'anmen Hospital, China Academy of Chinese Medical Sciences 2018 S413Scientific and Technological Innovation Project of the China Academy of Chinese Medical Sciences C12021A03320
6 · The paper itself

Abstract

backgroundMechanical analysis of the femoral head is mostly conducted through finite element analysis (FEA), the operation of which is relatively complex. In this study, the correlation between computed tomography (CT) quantitative analysis and FEA in the diagnosis of osteonecrosis of the femoral head (ONFH) was analyzed.

methodsThis retrospective study involved 30 hips from patients with Steinberg stage II ONFH who had not received treatment. The average CT density was measured, and an FEA model was constructed on the basis of the CT images of each case. The correlation between the average CT density and the FEA measurements was analyzed.

resultsThe average CT density of the coronal midline plane was 370.47 ± 16.85 HU, and that of the maximum necrotic layer was 420.73 ± 22.24 HU. According to the FEA results, the maximum total displacement was 0.42 ± 0.04 mm, the maximum displacement in the Z direction was 0.25 ± 0.02 mm, the maximum equivalent stress in the stress concentration zone of the head was 1.81 ± 0.02 MPa, and the failure coefficient was 0.34 ± 0.02. The average CT density of the maximum necrotic layer was not correlated with the maximum total displacement or maximum displacement in the Z direction but was correlated with the maximum equivalent stress (r = 0.65; P < 0.1001) and failure coefficient (r=-0.58; P < 0.001). The average CT intensity of the maximum slice (P = 0.004) and the average failure coefficient (P = 0.020) significantly differed between the collapse and noncollapse groups.

conclusionCT quantification can reflect the load distribution and bearing capacity of ONFH to some extent. The higher the average CT density of the maximum slice, the lower are the average failure coefficient of the femoral head and the clinical risk of collapse.

Indexed as

Femur HeadFemur Head NecrosisFinite Element AnalysisTomography, X-Ray ComputedAdultBiomechanical PhenomenaFemaleHumansMaleMiddle AgedRetrospective StudiesStress, MechanicalYoung AdultCT densityFemoral head necrosisFinite element analysisImagingMechanical analysis

Identifiers

PMID42067848
PMCPMC13312509

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