Evidence map›Paper›PMID 42067682›Full record

ArticleAnnals of hematology2026

Serositis as possible manifestation in MDS/AML patients with complex karyotype and TP53 mutation: case series.

Eleonora Gugole, Edoardo Tamellini, Sara Jance, Nicola Serafin, Pietro Antonini, Chiara Colato, Mauro Krampera, Isacco Ferrarini, Ilaria Tanasi

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PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eleonora GugoleHematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, University of Verona, Verona, Italy.
Edoardo TamelliniHematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, University of Verona, Verona, Italy.
Sara JanceHematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, University of Verona, Verona, Italy.
Nicola SerafinHematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, University of Verona, Verona, Italy.
Pietro AntoniniSection of Pathology, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
Chiara ColatoSection of Pathology, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
Mauro KramperaHematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, University of Verona, Verona, Italy.
Isacco FerrariniHematology and Bone Marrow Transplant Unit, Section of Biomedicine of Innovation, Department of Engineering for Innovative Medicine, University of Verona, Verona, Italy. isacco.ferrarini@univr.it.ORCID http://orcid.org/0000-0001-9867-8335
Ilaria TanasiHematology and Bone Marrow Transplant Unit, Department of Medicine, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelodysplastic syndromes (MDS) and Acute Myeloid Leukemia (AML) are increasingly recognized to exhibit immune dysregulation, which can occasionally present with autoinflammatory manifestations. We describe four patients with MDS/AML harboring p53 mutations and a complex karyotype who developed inflammatory serositis without infectious correlation. All patients showed clinical improvement following corticosteroid therapy.

Indexed as

Leukemia, Myeloid, AcuteMutationMyelodysplastic SyndromesSerositisTumor Suppressor Protein p53AdultAgedFemaleHumansKaryotypeMaleMiddle AgedTP53 protein, humanTumor Suppressor Protein p53Complex karyotypeMDS/AMLSerositisSteroid therapyTP53 mutation

Identifiers

PMID42067682
PMCPMC13135004

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.