Evidence map›Paper›PMID 42067504›Full record

ArticleThoracic cancer2026

Evaluating the Role of Advanced Age and Risk Factors in Postoperative Outcomes Following Major Lung Cancer Resection.

Fuad Damirov, Javad Karimbayli, Junli Ke, Mircea Gabriel Stoleriu, Ughur Aghamaliyev, Sascha Dreher, Enole Boedeker, Sibylle Gerz, Rudolf Alexander Hatz, Gerhard Preissler

Abstract read
In one paragraph

Article in Thoracic cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fuad DamirovDepartment of Thoracic Surgery, Ludwig Maximilian University of Munich (LMU), Munich, Germany.ORCID https://orcid.org/0000-0001-6982-2369
Javad KarimbayliDivision of Molecular Oncology, Centro di Riferimento Oncologico (CRO) of Aviano, IRCCS, National Cancer Institute, Aviano, Italy.
Junli KeDepartment of Thoracic Surgery, Ludwig Maximilian University of Munich (LMU), Munich, Germany.
Mircea Gabriel StoleriuDepartment of Thoracic Surgery, Ludwig Maximilian University of Munich (LMU), Munich, Germany.
Ughur AghamaliyevDepartment of General, Visceral and Transplantation Surgery, Ludwig Maximilian University of Munich (LMU), Munich, Germany.
Sascha DreherDepartment of Thoracic Surgery, Robert Bosch Pulmonary Center Stuttgart, Robert Bosch Hospital, Bosch Health Campus, Stuttgart, Germany.
Enole BoedekerDepartment of Thoracic Surgery, Robert Bosch Pulmonary Center Stuttgart, Robert Bosch Hospital, Bosch Health Campus, Stuttgart, Germany.
Sibylle GerzDepartment of Thoracic Surgery, Robert Bosch Pulmonary Center Stuttgart, Robert Bosch Hospital, Bosch Health Campus, Stuttgart, Germany.
Rudolf Alexander HatzDepartment of Thoracic Surgery, Ludwig Maximilian University of Munich (LMU), Munich, Germany.
Gerhard PreisslerDepartment of Thoracic Surgery, Robert Bosch Pulmonary Center Stuttgart, Robert Bosch Hospital, Bosch Health Campus, Stuttgart, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of lung cancer increases with age. On average, patients diagnosed with lung cancer are about 70 years. It is known that older patients are more prone to complications after major lung resection due to physiological changes; however, there is still a lack of knowledge of predictive factors associated with a higher complication risk.

aimsIn this study the association of age and postoperative complication rates in lung cancer patients is analyzed. Further, predictors of postoperative complications in the era of minimally invasive surgery in older patients are identified.

methodsWe retrospectively analyzed 180 consecutive patients with pathologically proven lung adenocarcinoma and squamous cell carcinoma. Patients were categorized into septuagenarians and octogenarians. Univariate and multivariate analyses were conducted to detect risk factors of postoperative morbidity.

resultsThere were 141 (78.33%) and 39 patients (21.67%) in the septuagenarian group and octogenarian group, respectively. 67 (37.2%) patients experienced postoperative complications. The thirty-day mortality rate was 1.6%. The groups did not differ in terms of postoperative complications. Upon multivariate analysis, ECOG score ≥ 1 (p = 0.032), lowered FEV1/FVC (p = 0.029), and hypoalbuminemia (p = 0.027) were significant predictors for the development of major complications after lung cancer surgery.

conclusionAge over 80 years was not found to be an independent risk factor for the complication rates after lung cancer surgery. However, ECOG performance status ≥ 1, reduced FEV1/FVC, and lower serum albumin levels were independently associated with major postoperative complications.

Indexed as

Carcinoma, Squamous CellLung NeoplasmsPostoperative ComplicationsAgedAged, 80 and overAge FactorsFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTreatment Outcomelung cancerolder patientspostoperative complicationsserum albuminthoracic surgery

Identifiers

PMID42067504
PMCPMC13134944

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.