Evidence map›Paper›PMID 42067273›Full record

ReviewEndocrinology and metabolism clinics of North America2026

Pheochromocytomas and Paragangliomas.

Hussam Alkaissi, David Taieb, Hans K Ghayee

Abstract readReview
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hussam AlkaissiNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
David TaiebDepartment of Nuclear Medicine, Aix-Marseille University, La Timone University Hospital, Marseille, France.
Hans K GhayeeDivision of Endocrinology and Metabolism, Department of Medicine, University of Florida, Endocrinology and Metabolism, North Florida/South Georgia VA Health System, 1600 Southwest Archer Road, Suite H-2, Gainesville, FL 32608, USA. Electronic address: hans.ghayee@medicine.ufl.edu.

Funding

Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

PPGL are rare neuroendocrine tumors that secrete catecholamines. There are over 20 driver mutations associated with PPGL. All patients who have been diagnosed with PPGL need genetic testing. Diagnosis is made by checking either plasma or urine metanephrines. Localization studies include computed tomography, magnetic resonance imaging, and functional imaging such as positron emission tomography scans. Alpha-blockers are a central component for preparation prior to surgical removal of the tumor, which is the mainstay of therapy. For patients with metastatic disease, several different modalities can be employed from palliative surgery, chemotherapy, radionuclide therapy, HIF-2α inhibitor, and drugs in clinical trials.

Indexed as

Adrenal Gland NeoplasmsParagangliomaPheochromocytomaHumansCatecholaminesMetanephrinesParagangliomaPheochromocytomaPseudohypoxia

Identifiers

PMID42067273
PMCPMC13313079

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.