Evidence map›Paper›PMID 42067207›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie

Liver transplantation from donors following medical assistance in dying: a scoping review and retrospective cohort study.

Olivia Ganescu, Magan Solomon, Prosanto Chaudhury, Steven Paraskevas, Lindsay Hales, Myriam Martel, Peter Metrakos, George Zogopoulos, Jean Tchervenkov, Philip Wong and 2 more

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Olivia GanescuFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Magan SolomonFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Prosanto ChaudhuryFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Steven ParaskevasFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Lindsay HalesFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Myriam MartelFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Peter MetrakosFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
George ZogopoulosFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Jean TchervenkovFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Philip WongFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Alan BarkunFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun).
Jeffrey BarkunFrom the Division of General Surgery, McGill University Health Centre, Montréal, Que. (Ganescu, Chaudhury, Paraskevas, Metrakos, Zogopoulos, Tchervenkov, J. Barkun); the Department of Medicine, McGill University, Montréal, Que. (Solomon); the McGill University Health Centre Libraries, Montréal, Que. (Hales); the Division of Gastroenterology & Hepatology, Department of Medicine, McGill University Health Centre, Montréal, Que. (Martel, Wong, A. Barkun) jeffrey.barkun.med@ssss.gouv.qc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver transplantation from donors following medical assistance in dying (MAiD) is a novel practice with emerging Canadian outcomes data. We sought to compare donor and recipient outcomes after liver transplantation following donor MAiD, circulatory death (DCD), or brain death (DBD).

methodsWe conducted a scoping review and a single-centre retrospective cohort study.

resultsThe 5 retrospective studies identified found comparable short-term liver graft and patient survival between MAiD, DCD, and DBD liver recipients, with no differences in vascular complications or primary nonfunction. One study noted higher biliary complications among MAiD liver recipients. Our single-centre retrospective cohort reporting included 177 liver transplant recipients between 2018 and 2024 (19 MAiD, 14 DCD, and 144 DBD donors). Among donors, MAiD (mean age 59 yr) and DBD (mean age 57 yr) donors were older than DCD donors (mean age 37 yr;

conclusionLiver transplantation from donors who underwent MAiD was not associated with higher graft loss or mortality than in those who underwent DCD or DBD. Its continued use is safe, and larger multicentre studies are warranted for validation.

Indexed as

Liver TransplantationTissue DonorsAdultBrain DeathCanadaFemaleGraft SurvivalHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID42067207
PMCPMC13155884

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.