Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
15 authors.
Alberto MariniDepartment of Neuroscience, Section of Human Anatomy, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-7222-9056
Consuelo PitolliDepartment of Neuroscience, Section of Human Anatomy, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-9148-667X
Sabrina CicconeDepartment of Neuroscience, Section of Human Anatomy, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Marco PieraccioliDepartment of Neuroscience, Section of Human Anatomy, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0003-3995-535X
Chiara NaroDepartment of Neuroscience, Section of Human Anatomy, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-3135-3218
Fernando PalluzziBioinformatics Research Core Facility, Gemelli Science and Technology Park (GSTeP), IRCCS Fondazione Policlinico Universitario Agostino Gemelli, 00168 Rome, Italy.
Francesca NazioDepartment of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-3039-4448
Pamela BielliDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-3347-8345
Claudio SetteDepartment of Neuroscience, Section of Human Anatomy, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Vittoria PagliariniDepartment of Neuroscience, Section of Human Anatomy, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-2388-0675
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Back-splicing is a noncanonical splicing event driving circular RNA (circRNA) biogenesis. While its molecular mechanisms are partly known, global regulation in tumors remains unclear. Here, we uncover an hnRNP C-dependent mechanism that represses a broad repertoire of circRNAs in group 3 medulloblastoma (MB). HnRNP C binds
Indexed as
Alu ElementsHeterogeneous-Nuclear Ribonucleoprotein Group CMedulloblastomaRNA, CircularRNA PrecursorsTranscriptomeCell Line, TumorExonsGene Expression Regulation, NeoplasticHumansIntronsProtein BindingRNA SplicingHeterogeneous-Nuclear Ribonucleoprotein Group CRNA, CircularRNA Precursors
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
HnRNP C binding to inverted · full record | OpenQuestion