Evidence map›Paper›PMID 42066043›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Structural basis of iron piracy by human gut

Augustinas Silale, Yung Li Soo, Hannah Mark, Rachel N Motz, Arnaud Baslé, Elizabeth M Nolan, Bert van den Berg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Augustinas SilaleBiosciences Institute, Newcastle University, Faculty of Medical Sciences, Newcastle upon Tyne NE2 4HH, United Kingdom.ORCID 0000-0003-3338-2087
Yung Li SooBiosciences Institute, Newcastle University, Faculty of Medical Sciences, Newcastle upon Tyne NE2 4HH, United Kingdom.
Hannah MarkBiosciences Institute, Newcastle University, Faculty of Medical Sciences, Newcastle upon Tyne NE2 4HH, United Kingdom.ORCID 0009-0000-8456-9189
Rachel N MotzDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
Arnaud BasléBiosciences Institute, Newcastle University, Faculty of Medical Sciences, Newcastle upon Tyne NE2 4HH, United Kingdom.ORCID 0000-0002-4899-3086
Elizabeth M NolanDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139.
Bert van den BergBiosciences Institute, Newcastle University, Faculty of Medical Sciences, Newcastle upon Tyne NE2 4HH, United Kingdom.ORCID 0000-0003-1966-8804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron is an essential element that can be growth-limiting in microbial communities, particularly those present within host organisms. To acquire iron, many bacteria secrete siderophores, secondary metabolites that chelate ferric iron. These iron chelates can be transported back into the cell via TonB-dependent transporters in the outer membrane, followed by intracellular liberation of the iron. Pathogenic

Indexed as

Bacterial ProteinsBacteroides thetaiotaomicronIronSiderophoresBacterial Outer Membrane ProteinsBiological TransportCryoelectron MicroscopyHumansLipoproteinsMembrane ProteinsBacterial Outer Membrane ProteinsBacterial ProteinsIronLipoproteinsMembrane ProteinsSiderophorestonB protein, Bacteriagut microbiotairon piracylipoproteinTonB-dependent transporterxenosiderophores

Identifiers

PMID42066043
PMCPMC13142918

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.