Evidence map›Paper›PMID 42066028›Full record

ArticlePest management science2026

Alcoholic extracts of Russian sage (Salvia yangii) contain bioactive terpenoids with inhibitory activity against grapevine downy mildew (Plasmopara viticola).

Anna Smaldone, Oscar Giovannini, Martina Magni, Michael Oberhuber, Peter Robatscher, Michele Perazzolli

Abstract read
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna SmaldoneCenter for Agriculture Food Environment (C3A), University of Trento, San Michele all'Adige, Italy.
Oscar GiovanniniResearch and Innovation Centre, Fondazione Edmund Mach, San Michele all'Adige, Italy.
Martina MagniLaboratory for Flavours and Metabolites, Laimburg Research Centre, Laimburg 6, Pfatten (Vadena), Auer (Ora), Italy.
Michael OberhuberLaboratory for Flavours and Metabolites, Laimburg Research Centre, Laimburg 6, Pfatten (Vadena), Auer (Ora), Italy.
Peter RobatscherLaboratory for Flavours and Metabolites, Laimburg Research Centre, Laimburg 6, Pfatten (Vadena), Auer (Ora), Italy.ORCID https://orcid.org/0000-0002-3376-0562
Michele PerazzolliCenter for Agriculture Food Environment (C3A), University of Trento, San Michele all'Adige, Italy.ORCID https://orcid.org/0000-0001-7218-9963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlant extracts are promising eco-friendly alternatives to synthetic fungicides for developing sustainable plant protection strategies. Grapevine downy mildew, caused by Plasmopara viticola, is a devastating disease that requires frequent fungicide applications, making it an ideal target for plant-based products. Salvia officinalis extracts are known to reduce downy mildew severity, but little is known about the efficacy and chemical composition of other fast-growing Salvia species with low economic value. This study aimed to evaluate the efficacy of alcoholic extracts of Russian sage (Salvia yangii) against grapevine downy mildew and to annotate bioactive compounds against P. viticola.

resultsAlcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. In particular, leaf and flower extracts showed efficacy comparable to that of copper-based fungicides, whereas stem extract was only partially active. Shoot extracts were fractionated by preparative liquid chromatography (LC), and the activity of the resulting fractions was assessed against P. viticola using leaf disk assays. Untargeted metabolomic analyses revealed putative terpenoids as the main components of the active fractions, as determined by gas chromatography-mass spectrometry (GC-MS) and ultra-high-pressure liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) analyses. Specifically, 7-methylrosmanol, 12-O-methylcarnosic acid, carnosic acid, and carnosol were identified as the main bioactive compounds against P. viticola.

conclusionRussian sage represents a valuable source of bioactive compounds for sustainable plant protection. © 2026 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

Fungicides, IndustrialOomycetesPlant DiseasesPlant ExtractsSalviaTerpenesVitisFungicides, IndustrialPlant ExtractsTerpenesantifungalbioactive compoundsbioguided separationplant extractsPlasmopara viticolaSalvia yangiiuntargeted metabolomics

Identifiers

PMID42066028
PMCPMC13453268

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.