Evidence map›Paper›PMID 42065966›Full record

ArticleSTAR protocols2026

Protocol for the standardized design of Morris water maze experiments and statistical analysis using SPSS.

Xiao-Yun Hu, Meng-Jie Xu, Xiang-Hu Liu, Tian Xia, Qi-Gang Zhou, Jian-Dong Jiang, Jing Zhang

Abstract read
In one paragraph

Article in STAR protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiao-Yun HuDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Meng-Jie XuDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Xiang-Hu LiuDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Tian XiaDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Qi-Gang ZhouDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 210029, China; Department of Pharmacy of First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China. Electronic address: qigangzhou@njmu.edu.cn.
Jian-Dong JiangDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 210029, China. Electronic address: jang.jdong@163.com.
Jing ZhangDepartment of Clinical Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 210029, China. Electronic address: zj1984@njmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Morris water maze is a widely used paradigm for assessing spatial learning and memory in rodents; however, variability in procedures and analysis can lead to inconsistent results across laboratories. Here, we present a protocol for the standardized design of Morris water maze experiments and statistical analysis using SPSS. We describe procedures for preliminary screening of mice, spatial data acquisition, assessment of spatial working memory and reference memory, as well as detailed SPSS operation and result interpretation.

Indexed as

Maze LearningMorris Water Maze TestAnimalsData Interpretation, StatisticalMiceResearch DesignBehaviorcognitive NeuroscienceNeuroscience

Identifiers

PMID42065966
PMCPMC13141749

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.