Evidence map›Paper›PMID 42065932›Full record

Trial reportHealth literacy research and practice2026

Evaluating Whether Icons and Visual Elements Help or Hinder Understanding of Key Information for Research Studies: Results From a Randomized Trial.

Mary C Politi, Clara N Lee, Eliana C Goldstein, Krista E Cooksey, Jessica Mozersky, Ashley J Housten, Jingxia Lu, Shuang Wu, Molly Volkmar, Victor Catalan-Gallegos and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Health literacy research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mary C PolitiSchool of Public Health, Washington University in St. Louis, St. Louis, Missouri, USA.
Clara N LeeDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina.
Eliana C GoldsteinSchool of Public Health, Washington University in St. Louis, St. Louis, Missouri, USA.
Krista E CookseySchool of Public Health, Washington University in St. Louis, St. Louis, Missouri, USA.
Jessica MozerskyDepartment of Medicine, Division of General Medicine & Geriatrics.
Ashley J HoustenDepartment of Surgery, Division of Public Health Sciences.
Jingxia LuDepartment of Surgery, Division of Public Health Sciences.
Shuang WuDepartment of Surgery, Division of Public Health Sciences.
Molly VolkmarWashington University School of Medicine, St. Louis, Missouri; Department of Communication.
Victor Catalan-GallegosDepartment of Surgery, Division of Plastic and Reconstructive Surgery, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina.
Kimberly A KaphingstWashington University School of Medicine, St. Louis, Missouri; Department of Communication.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
SURGICAL ONCOLOGY TRAINING GRANTT32CA009621 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN, William E. Gillanders · 1988 to 2026
$12.9M
NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NCI NIH HHS T32 CA009621
6 · The paper itself

Abstract

objectiveInformed consent forms for research are often lengthy and complex. One way to improve consent forms is to clarify the key information page required for federally funded research in the United States. We developed a visual key information page using color, plain language, bulleted text, and icons. In formative studies, the visual key information page was positively received, but some asked whether icons improve outcomes or distract from information. This study tested whether icons affect knowledge, satisfaction, or engagement with study information.

methodsWe recruited English-speaking, U.S.-based adults through Prime Panels. Participants were randomized to view one of three versions of a key information page about a hypothetical biobank study: Version A used bulleted, plain language text organized in boxes, incorporating icons and visual elements; Version B was identical but with no icons or other visual elements; Version C displayed identical plain language text only. We measured participants' intention to join the study, decisional conflict about choice intention, knowledge of study details, satisfaction with the information, and engagement with the information. Finally, they viewed all versions and reported their preference among the three and their attitudes about icons in Version A. KEY

resultsA total of 453 participants responded; we analyzed 422 valid responses. There were no significant differences in outcomes by version (all

conclusionsAlthough participants preferred icons and visual elements over text alone, icons and visual elements did not affect knowledge, satisfaction, or engagement with study information. Future research will investigate whether and how visual key information enhances text-based consent forms in a multisite randomized trial with ongoing studies.

Indexed as

Consent FormsHealth LiteracyInformed ConsentAdolescentAdultAgedAged, 80 and overBiological Specimen BanksComprehensionFemaleHumansMaleMiddle AgedUnited StatesYoung Adult

Identifiers

PMID42065932
PMCPMC13124231

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.