Evidence map›Paper›PMID 42065931›Full record

ArticleThe veterinary quarterly2026

Milk extracellular vesicles reveal insulin resistance status in peripartum dairy cows.

Madhusha Prasadani, Hanno Jaakson, Priit Karis, Subhashini Muhandiram, Merike Henno, Sirje Kuusik, Katri Ling, Harinda Rajapaksha, Meelis Ots, Aneta Andronowska and 3 more

Abstract read
In one paragraph

Article in The veterinary quarterly, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Madhusha PrasadaniInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Hanno JaaksonInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Priit KarisInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Subhashini MuhandiramInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Merike HennoInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Sirje KuusikInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Katri LingInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Harinda RajapakshaOracle for Research, Japan & Asia Pacific Region, Oracle Australia, Melbourne, Victoria, Australia.
Meelis OtsInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Aneta AndronowskaInstitute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
Suranga Pradeep KodithuwakkuInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
Vallo VolkeDepartment of Pathophysiology, Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, Tartu, Estonia.
Alireza FazeliInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transition from gestation to lactation is a critical period that leads to insulin resistance (IR) in dairy cows. IR detection requires invasive sampling and laborious methods; therefore, novel and non-invasive approaches are essential. Extracellular vesicles (EVs) are nano-sized particles released by cells and are linked to disease pathophysiology. Hence, the present study aimed to explore the potential application of cow milk EVs (MEVs) in detecting IR in dairy cows. An intravenous glucose tolerance test (IVGTT) was performed (

Indexed as

BiomarkersCattle DiseasesExtracellular VesiclesFatty AcidsInsulin ResistanceMilkAnimalsCattleChromatography, GelFemaleGlucose Tolerance TestLactationPregnancyProteomeWheyBiomarkersFatty AcidsProteomedairy cowsdiagnosis and monitoringextracellular vesiclesinsulin resistancelong-chain fatty acidsMilkparticle diameterproteome

Identifiers

PMID42065931
PMCPMC13137739

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.