Evidence map›Paper›PMID 42065854›Full record

ArticleMolecular neurobiology2026

Impaired Development of the Medial Olivocochlear System in a KCNQ4-Deficient Mouse Model.

Ezequiel Rías, Ingrid Ouwerkerk, Guillermo Spitzmaul, Leonardo Dionisio

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ezequiel RíasLaboratorio de Canales Iónicos, Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB), CONICET-UNS, Camino La Carrindanga Km 7, Bahía Blanca, Argentina.ORCID http://orcid.org/0009-0000-6324-4561
Ingrid OuwerkerkLaboratorio de Canales Iónicos, Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB), CONICET-UNS, Camino La Carrindanga Km 7, Bahía Blanca, Argentina.
Guillermo SpitzmaulLaboratorio de Canales Iónicos, Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB), CONICET-UNS, Camino La Carrindanga Km 7, Bahía Blanca, Argentina.ORCID http://orcid.org/0000-0001-5123-8914
Leonardo DionisioLaboratorio de Canales Iónicos, Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB), CONICET-UNS, Camino La Carrindanga Km 7, Bahía Blanca, Argentina. ldionisio@inibibb-conicet.gob.ar.ORCID http://orcid.org/0000-0002-2896-4317

Funding

Agencia Nacional de Promoción Científica y Tecnológica (PICT 2021-0545)Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación (PICT 2021-0145)Consejo Nacional de Investigaciones Científicas y Técnicas (PIBAA 0769)Consejo Nacional de Investigaciones Científicas y Técnicas (PIP 0091)Universidad Nacional del Sur (PGI 24/B262)Universidad Nacional del Sur (PGI 24/ZB98)
6 · The paper itself

Abstract

The medial olivocochlear (MOC) efferent system modulates outer hair cell (OHC) excitability and protects cochlea from overstimulation. Cholinergic activation of α9α10 nicotinic acetylcholine receptors (nAChRs) triggers Ca⁺

Indexed as

CochleaGene Expression Regulation, DevelopmentalKCNQ Potassium ChannelsOlivary NucleusAnimalsHair Cells, Auditory, OuterMiceMice, KnockoutProtein BindingSynapsesKcnq4 protein, mouseKCNQ Potassium ChannelsEfferent terminalsInner earKCNQ4Outer hair cell

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.