Evidence map›Paper›PMID 42065814›Full record

ArticleIrish journal of medical science2026

A retrospective case series of primary spinal tumours at the national spinal injuries unit.

Ella Flaherty, Emelia Deane, Jake McDonnell, Tiarnán Ó Conaill, Sandra O'Malley, Cathleen O'Neill, Grainne Cunnife, Joseph Butler, Seamus Morris, Stacey Darwish

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Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ella FlahertyUCD School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Emelia DeaneDepartment of Surgery, University of Galway, Galway, Ireland. edeane@tcd.ie.ORCID http://orcid.org/0009-0001-0982-1919
Jake McDonnellNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.
Tiarnán Ó ConaillNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.
Sandra O'MalleyNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.
Cathleen O'NeillNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.
Grainne CunnifeNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.
Joseph ButlerNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.
Seamus MorrisNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.
Stacey DarwishNational Spinal Injuries Unit, Mater Misericordiae University Hospital, Eccles St., Dublin 7, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary extradural tumours of the spine are a rare group of spinal tumours. Current literature reporting demographic variables and prognostic information is limited. No prior Irish database has comprehensively compiled this data.

aimsTo create the first database in Ireland reporting the demographics and outcome information of extradural spinal tumours in Ireland.

methodsRetrospective case series analysing population-based data from the National Spinal Injuries Unit from 1992-2021. ICD-10 codes C41.2 and C41.4 were used to extract data from the Mater Misericordiae University Hospital databases, reporting demographics, treatment, and survival outcomes.

results31 extradural spinal tumours were identified. Chondrosarcomas were the most common tumour subtype (26%), with chordomas and giant cell tumours both the second most common subtypes (16%). The thoracic spine was the predominant location (51.6%). The mean patient age was 44.4 years, with a male predominance (65%). Surgical excision was performed in all cases, with a complication rate of 74.2% and a recurrence of 48.4%. Cervical tumours had significantly higher recurrence (100%) than non-cervical (40.7%, p = 0.043). Overall mortality was 22.6%, with 5-year survival highest for cervical and sacral tumours (100%) and lowest for lumbar (66.7%) and thoracic tumours (72.2%).

conclusionPrimary extradural spinal tumours are rare tumours but impose a significant healthcare burden, as evidenced by prolonged hospital stays and complication rates. Management requires a multidisciplinary approach in a specialist centre. The underutilisation and variability of adjuvant therapies in this cohort underscores the need for further research and development of standardised multimodal treatment protocols.

Indexed as

ChondrosarcomaChordomaExtradural spinal tumoursPrimary Spinal TumoursSpinal surgerySpinal tumour epidemiologySurgical outcomes

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.