Evidence map›Paper›PMID 42065726›Full record

ArticleInternational orthopaedics2026

Bioinductive scaffold augmentation of the patellar tendon: a scoping review of indications, techniques and early outcomes.

Karim Khaled, Anas Elshoura, Merve Bozer Kavaku, Emmanouil Papakostas

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Karim Khaled *County Durham and Darlington NHS Foundation Trust, Darlington, United Kingdom. Karim.khaled@nhs.net.
Anas Elshoura *South Tees Hospitals NHS Foundation Trust, Middlesbrough, United Kingdom.
Merve Bozer KavakuDepartment of Orthopaedics and Traumatology, Kaman State Hospital, Kirsehir, Turkey.
Emmanouil PapakostasDepartment of Orthopaedic Surgery, Aspetar, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis scoping review aimed to collate and synthesize reports of bioinductive scaffold augmentation for patellar tendon pathology, focusing on indications, surgical techniques, and early outcomes. Additionally, it aimed to contextualize these findings through the more established rotator cuff literature and consider tendon property variation to inform future research and implant development.

methodsA scoping review was conducted in accordance with PRISMA-ScR guidance. PubMed, Embase, Scopus, and Web of Science were searched from inception to 25 December 2025 for human studies of bioinductive scaffold augmentation in patellar tendon pathology. Two reviewers screened studies and extracted data. Findings were synthesized narratively and in tables.

resultsThe search identified 633 records, with ten studies ultimately included (6 technical notes, 3 case reports, and 1 case series), published between 2019 and 2025. Across all reports, 47 patients were described (ages 17-50; 76% male where reported); most studies used scaffolds for acute patellar tendon rupture (7/10), with fewer addressing chronic tendinopathy (3/10). Augmentation was most often indicated for poor tissue quality in rupture settings, revision after re-rupture, or persistent symptoms after failed conservative management in tendinopathy. Implants comprised a bovine Achilles tendon-derived collagen scaffold (6 studies), a decellularized human dermal allograft (2), a collagen-PLLA composite scaffold (1), and an autologous platelet-rich fibrin matrix construct (1). Post-operative rehabilitation was variably reported. Reported clinical outcomes were limited but suggested some improvements in pain, functional scores and MRI appearance.

conclusionThe adoption of bioinductive scaffold augmentation in patellar tendon surgery may be considered theoretically plausible. However, fundamental pre-clinical biomechanical and histological work in human(-cadaveric) models is not available at present, and longitudinal (comparative) clinical research is ultimately needed to investigate the effects of this application, and allow for the meaningful interpretation of results. The intrinsic mechanical and biological properties of the patellar tendon warrant a more nuanced consideration in technique standardization and future device iterations.

Indexed as

Patellar LigamentTendinopathyTendon InjuriesTissue ScaffoldsAdultFemaleHumansMaleMiddle AgedRuptureTreatment OutcomeBioinductive scaffoldCollagen scaffoldPatellar tendinopathyPatellar tendonPatellar tendon ruptureTendon augmentationTissue engineering

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.