Observational studyInvestigative and clinical urology2026
Disease complexity, not surgical approach, predicts outcomes in xanthogranulomatous pyelonephritis.
Observational study in Investigative and clinical urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeXanthogranulomatous pyelonephritis (XGP) is a destructive renal infection typically requiring nephrectomy. Although laparoscopy is increasingly feasible, morbidity remains high and predictors of adverse outcomes are not well defined. We aimed to explore predictors of postoperative complications and compare laparoscopic versus open approaches. MATERIALS AND
methodsWe retrospectively analyzed 42 XGP nephrectomies (2014-2024) at a tertiary referral center. Demographics, imaging features, intraoperative findings, and 30-day outcomes were collected. Complications were graded by Clavien-Dindo, defining major complications as grade ≥III. Comparative analyses used nonparametric and exact tests; exploratory regression identified pre- and intraoperative predictors.
resultsMedian age was 47.0 years; 78.6% were females. Laparoscopy was attempted in 32 cases, with 5 conversions (15.6%). Overall, 69.0% experienced complications and 50.0% major events, but no deaths occurred. Compared with open surgery (n=10), laparoscopy showed lower transfusion requirements (34.4% vs. 60.0%) and less blood loss, while overall complication rates were similar. Hydronephrosis, perinephric/psoas abscesses, and higher blood loss were associated with increased morbidity.
conclusionsXGP nephrectomy remains a high-morbidity operation. Laparoscopy appears feasible and safe in selected cases, with trends toward reduced transfusion and blood loss. Disease complexity-rather than surgical approach-primarily drives outcomes. These exploratory findings warrant validation in multicenter studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.