Evidence map›Paper›PMID 42065655›Full record

ArticleJournal of neurophysiology2026

Contrast and pattern adaptation in visual cortex share a common gain control mechanism.

S Amin Moosavi, Elaine Tring, Dario L Ringach

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

S Amin MoosaviDepartment of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States.ORCID 0000-0002-8862-789X
Elaine TringDepartment of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States.
Dario L RingachDepartment of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States.ORCID 0000-0001-6439-334X

Funding

Origins of plasticity in the establishment of binocular visionR01EY023871 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Joshua Trachtenberg · 2013 to 2026
$5.4M
Thalamic constraints on cortical organizationR01EY034488 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RINGACH, DARIO L · 2023 to 2025
$1.8M
Population codes and sensory discriminationR01NS116471 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RINGACH, DARIO L · 2023 to 2024
$789k
Visual function of transcriptomically defined glutamatergic neuronsR21EY036219 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RINGACH, DARIO L · 2024 to 2025
$426k
Cortical adaptation in neural populationsR21EY035064 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RINGACH, DARIO L · 2024 to 2025
$424k
HHS | NIH | National Eye Institute (NEI) EY034488HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS116471NEI NIH HHS R01 EY023871NEI NIH HHS R01 EY034488NEI NIH HHS R21 EY035064NEI NIH HHS R21 EY036219NINDS NIH HHS R01 NS116471
6 · The paper itself

Abstract

Neuronal populations in primary visual cortex adapt both to stimulus contrast and to the probability of occurrence of visual patterns. Previous work showed that the magnitude of the population response follows a separable power-law function of contrast and stimulus probability, suggesting the existence of a shared gain mechanism. Here we ask whether a similar equivalence extends beyond response magnitude to the full distribution of activity across neurons within a trial. Across a wide range of adaptation states, we find that population responses are highly sparse and well described by a zero-inflated log-normal distribution. In this model, a fraction

Indexed as

Adaptation, PhysiologicalContrast SensitivityModels, NeurologicalNeuronsPattern Recognition, VisualPrimary Visual CortexVisual CortexAnimalscontrast adaptationcontrast gainlong-tailed population responsespattern adaptationvisual adaptation

Identifiers

PMID42065655
PMCPMC13222541

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.