Evidence map›Paper›PMID 42065223›Full record

ReviewEFORT open reviews2026

Multiligament-injured knee: what the general orthopedic surgeon should know.

Michael Hantes, Vasileios Raoulis, Aristeidis Zibis, Nikolaos Metaxiotis, Artemis Hante, Nikolaos Stefanou, Vasileios S Akrivos

Abstract readReview
In one paragraph

Review in EFORT open reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Research progress in diagnosis and treatment of multiple ligament knee injuries].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael HantesDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.ORCID https://orcid.org/0000-0001-9494-6048
Vasileios RaoulisDepartment of Anatomy, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Aristeidis ZibisDepartment of Anatomy, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Nikolaos MetaxiotisDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Artemis HantePhysiotherapy Department, International Hellenic University, Thessaloniki, Greece.
Nikolaos StefanouDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Vasileios S AkrivosDepartment of Orthopaedic Surgery and Musculoskeletal Trauma, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiligament knee injuries (MLKIs) are rare but severe injuries involving bicruciate or collateral ligament disruption, frequently associated with knee dislocation, fractures, and neurovascular compromise. Vascular injury occurs in a mean of approximately 18% of cases and may be present despite palpable pulses; an ankle-brachial index (ABI) < 0.9 demonstrates high sensitivity for arterial injury. Peroneal nerve injury occurs in approximately 10-40% of cases. Early recognition and structured evaluation are critical. Serial vascular examinations, selective CT angiography, and careful neurologic assessment are mandatory. General orthopedic surgeons often make the initial management decisions, and timely diagnosis, stabilization, and referral significantly influence limb salvage and long-term function. The Schenck KD classification remains standard, with recent consensus refinements to the KD V category and proposed modifiers such as '-EM' for extensor mechanism disruption. Associated meniscal, chondral, and rare entities, such as uniplanar coronal tibiofemoral subluxation, require high clinical suspicion. Knee-spanning external fixation is indicated in vascular injury, open or fracture-dislocations, soft-tissue compromise, or persistent instability, with reconstruction commonly performed later at 3-6 weeks. Current evidence shows no clear superiority of early versus delayed reconstruction in functional outcomes, although early surgery increases stiffness risk. Anatomic reconstruction is generally favored over repair for high-grade PLC and MCL injuries due to lower failure and complication rates. At 2 years, patients retain approximately 80-85% of knee function; however, a gradual functional decline over time is observed. Arthrofibrosis (≈10%) remains the most common complication.

Indexed as

ACLcollateral ligamentsknee dislocationmultiligament knee injuryorthopedic traumaPCL

Identifiers

PMID42065223
PMCPMC13150330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.