Evidence map›Paper›PMID 42064981›Full record

ArticleFrontiers in neurology

New-onset constipation at acute stage after stroke: incidence, risk factors, and impact on stroke rehabilitation.

Zhaoyang Lv, Shiyu Fan, Xv Ma, Feng Liu, Hao Wu, Zhihong Shi, Meng Wang, Tao Yu, Pan Wang, Shuai Liu and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07751224 (Effectiveness of Auricular Acupuncture for Post-Stroke Constipation), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07751224 nacompletednot on this map

Effectiveness of Auricular Acupuncture for Post-Stroke Constipation: A Randomized Sham-Controlled Trial

TypeinterventionalSponsorHo Chi Minh City Orthopedics and Rehabilitation HospitalRan2024 to 2025Enrolled60ConditionsConstipation, Stroke, Post-stroke ConstipationArmsAuricular Acupuncture, Sham Auricular Acupuncture
3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Zhaoyang Lv *Department of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Shiyu Fan *National Clinical Medical Research Center of Acupuncture, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xv MaDepartment of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Feng LiuDepartment of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Hao WuDepartment of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Zhihong ShiDepartment of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Meng WangNational Clinical Medical Research Center of Acupuncture, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Tao YuNational Clinical Medical Research Center of Acupuncture, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Pan WangDepartment of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Shuai LiuDepartment of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Yong JiDepartment of Neurology, Tianjin Key Laboratory of Cerebral Blood Flow Reconstruction and Head and Neck Tumor New Technology Translation, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The rapid increase in the global aging population poses a major public health challenge due to the prevalence of stroke. Constipation represents a significant complication of stroke, significantly impacting quality of life. The objective of this study is to investigate the incidence of constipation in acute stroke and to identify the factors that contribute to new-onset constipation (defined as constipation developing after stroke in patients with no prior history) after stroke. Methods: A total of 600 acute stroke patients were recruited for a cross-sectional study, with a questionnaire administered to each participant. This study included demographic characteristics, stroke type and focus, medical history, sleep quality, psychological problems, and the NIHSS and Barthel index (BI). Participants with constipation were evaluated for severity, medications, and stroke outcomes at discharge by the investigators. Results: Of the 600 acute stroke patients, 126 (21%) reported a history of constipation. Furthermore, 278 patients (46.3%) demonstrated post-stroke constipation (PSC), while 184 patients (38.8%) experienced new-onset constipation following their stroke. The results indicated that hemorrhagic stroke, posterior circulation stroke, diabetes, osmotic diuretics, antacids, use of bedpans, Difficulty falling asleep, depression, and a higher NIHSS score at admission were significant risk factors for new-onset constipation. In patients demonstrating moderate severity, PSC correlated with adverse stroke outcomes at discharge. Conclusion: The incidence of constipation in acute stroke patients is higher than that in the general population. The results suggest that depression and Difficulty falling asleep may increase the risk of new-onset constipation. Moreover, after adjusting for confounders, new-onset constipation was independently associated with poor discharge outcome, particularly in patients with moderate stroke severity. Early identification of constipation risk in stroke patients can improve the development and optimization of rehabilitation protocols. Clinical trial registration: Identifier ChiCTR2400080663.

Indexed as

constipationcross-sectional studyrehabilitationrisk factorsstroke

Identifiers

PMID42064981
PMCPMC13126731

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