Evidence map›Paper›PMID 42064934›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Plasma proteomics of

Amy Packer, Tahsina Khatun, James W Groves, Tony Wyss-Coray, Jonathan M Schott, Petroula Proitsi, Emma L Anderson, Dylan M Williams

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amy PackerUnit for Lifelong Health & Ageing, University College London, London, UK.ORCID 0000-0003-3783-1943
Tahsina KhatunUnit for Lifelong Health & Ageing, University College London, London, UK.
James W GrovesDementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Tony Wyss-CorayWu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.ORCID 0000-0001-5893-0831
Jonathan M SchottDementia Research Centre, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Petroula ProitsiCentre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Emma L AndersonDivision of Psychiatry, University College London, London, UK.
Dylan M WilliamsUnit for Lifelong Health & Ageing, University College London, London, UK.

Funding

Molecular signature of parabiosisR01AG072255 · NIA · STANFORD UNIVERSITY · PI WYSS-CORAY, TONY · 2021 to 2025
$2.4M
NIA NIH HHS R01 AG072255
6 · The paper itself

Abstract

Background: The apolipoprotein E ( Methods: In primary modelling, we analysed associations of Results: We identified 351 proteins associated with ε2 carriage and 480 with ε4 carriage among individuals of European ancestry ( Conclusion:

Indexed as

age-specific effectsAlzheimer’s diseaseAPOE genotypeblood-based biomarkersgenetic epidemiologyplasma proteomics

Identifiers

PMID42064934
PMCPMC13127520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.