ArticleFrontiers in clinical diabetes and healthcare2026
Prevalence of infection in amputations in patients with diabetic foot ulcer: a retrospective study.
Article in Frontiers in clinical diabetes and healthcare, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the prevalence of infection in diabetic foot ulcers (DFUs) and its association with lower limb major and minor amputations, examining demographic and socioeconomic factors influencing DFU outcomes. Research design and methods: This retrospective study analyzed data from the Indiana Network for Patient Care (INPC) from January 2019 to May 2024. A total of 27,078 patients with DFUs were included, aged 9 to 103 years. Data included demographics, clinical encounters, ICD-10, CPT codes, laboratory values, and microbiological assessments. Analyses included Pearson correlation, logistic regression, and one-sample proportion tests. Results: Patients were predominately male (64.3%) and female (35.7%) with a mean age of 63.8 years. DFU prevalence showed significant inverse correlation with median income (r=0.2108, p=0.0016); lower-income areas (median income < $64,200) had DFU rates > 5.0 per 1,000 population. Of cultured specimens, 33.79% showed infections, primarily Conclusions: Bacterial infections, particularly
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