Evidence map›Paper›PMID 42064838›Full record

ReviewNeuroscience applied2026

Special characteristics of human astrocytes and their roles in brain homeostasis.

Ilari Kousa, Karo Talvio, Ulla-Kaisa Peteri, Maija L Castrén

Abstract readReview
In one paragraph

Review in Neuroscience applied, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ilari KousaDepartment of Physiology, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland.
Karo TalvioDepartment of Physiology, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland.
Ulla-Kaisa PeteriDepartment of Physiology, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland.
Maija L CastrénDepartment of Physiology, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00290, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human astrocytes differ morphologically, functionally, and in their gene expression patterns from murine astrocytes. The astrocytic heterogeneity and complexity observed in the mouse brain are multiplied in humans, evident in primate-specific astrocyte populations and region-specific subtypes reflecting diverse molecular programs and environmental factors in the human brain. Astrocytes also contribute to the evolutionary processes associated with an increase in brain size and enhancing cognitive function. In this review, astrocyte differentiation and function are described to frame the processes that make human astrocytes specific, and whose disturbances can lead to brain pathology, as revealed by rapidly-evolving stem cell-based technology employed in human astrocyte studies.

Indexed as

AstrocytesHumaniPSCOrganoids

Identifiers

PMID42064838
PMCPMC13126458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.