Evidence map›Paper›PMID 42064824›Full record

ArticleInternational journal of dentistry2026

Synergistic Roles of Fimbriae and Gingipain Genotypes in

Manohar Kugaji, Kishore Bhat, Uday Muddapur, Ram Surath Kumar, Suman Kumar Ray, Eswar Kandaswamy, Vinayak Joshi

Abstract read
In one paragraph

Article in International journal of dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synergistic Roles of Fimbriae and Gingipain Genotypes inInternational journal of dentistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manohar KugajiCentral Research Laboratory, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, 590010, Karnataka, India.ORCID https://orcid.org/0000-0001-6315-4531
Kishore BhatArihant Hospital, Belagavi, 590010, Karnataka, India.ORCID https://orcid.org/0000-0002-9563-2531
Uday MuddapurDepartment of Biotechnology, KLE's BVB College of Engineering and Technology, Hubballi, 580031, Karnataka, India.ORCID https://orcid.org/0000-0003-3463-1989
Ram Surath KumarDepartment of Public Health Dentistry, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, 590010, India.ORCID https://orcid.org/0000-0001-7866-6038
Suman Kumar RayCentral Research Laboratory, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, 590010, Karnataka, India.ORCID https://orcid.org/0000-0003-2019-962X
Eswar KandaswamyDepartment of Periodontics, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA, lsu.edu.ORCID https://orcid.org/0000-0002-6661-7930
Vinayak JoshiDepartment of Periodontics, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA, lsu.edu.ORCID https://orcid.org/0000-0001-6215-4636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Materials and Methods: This secondary analysis included 120 subgingival plaque samples from patients with periodontitis. Fimbriae ( Results: The Conclusion: Specific fimbriae and gingipain genotypes co-occur and are linked to increased bacterial load suggesting synergistic roles in the pathogenicity of Clinical Relevance: The integration of microbial virulence profiling with host immune response characterization may improve risk stratification and enable the development of personalized periodontal care strategies. Furthermore, microbial genotypic profiling may support the identification of disease-specific targets, thereby facilitating the implementation of tailored therapeutic interventions for effective periodontitis management.

Indexed as

clinical severityfimbriaegingipain genotypesperiodontitisp. gingivalisvirulence

Identifiers

PMID42064824
PMCPMC13125940

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.