ArticleJournal of Indian Association of Pediatric Surgeons
Seroprevalence of Common Viruses in Early Infancy in North Indian Children with Biliary Atresia.
Article in Journal of Indian Association of Pediatric Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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5 authors.
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Abstract
Introduction: The link between viral infections and biliary atresia (BA), including their frequency and age of onset, remains unclear. Despite India's large population, research on this association is limited. Materials and Methods: In this study, 78 infants with BA and 35 age-matched controls were tested for Cytomegalovirus (CMV), Epstein-Barr virus (EBV), Rotavirus (RoV), and Reovirus (ReV) using enzyme-linked immunosorbent assay (ELISA) and quantitative real-time polymerase chain reaction. Results: Active viral infections were detected in 64.1% of BA patients, evidenced by viral DNA, antigens, or elevated immunoglobulin M antibodies. CMV was the most common, present in 40% of cases, while EBV was present in 19%. RoV and ReV antigens were identified in 25.6% and 29.5% of patients, respectively. Moreover, 98.7% of BA cases had IgG antibodies to one or more viruses, versus 54.3% in controls ( Conclusion: A high rate of viral exposure in BA highlights the need for further research in this area.
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