ReviewChemical & biomedical imaging2026
Single-Molecule Fluorescence Defines a New Dye Chemistry.
Review in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Imaging from Macro to Nanoscale: Multimodal Advances in Chemical and Biomedical Imaging.Chemical & biomedical imaging · 2026Review
- Fluorescent Diarylethenes With Polar Groups: Synthesis, Spectra, and Optical Microscopy Applications.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Century-old fluorescent dyes have regained life in the wave of super-resolution microscopy. The achievement of single-molecule resolution transcends conventional ensemble averaging, imposing specific photophysical requirements on fluorescent dyes at a millisecond temporal resolution and ∼1 nm single-molecule spatial precision. This review aims to synthesize the fundamental principle governing single-molecule fluorescence in terms of single-molecule photon flux, switching kinetics, and the structure-function correlations. It emphasizes the role of structural modulation down to the atomic level for tuning single-molecule fluorescence characteristics to enhance imaging resolutions and proposes a taxonomy of landmark structural modifications for regulating single-molecule fluorescence. The analysis would provide guidelines for ongoing dye engineering efforts to develop next-generation dyes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.