Evidence map›Paper›PMID 42064585›Full record

ArticleScientifica2026

Dhrubo Ahmed Khan, Mohammad Ashik Sheikh, Raihan Rahman Imon, Md Imtiaz, Shamin Ahmed, Harasit Gharami, Ryan V Labana, Tajudeen O Jimoh, Anand Gaurav, Maria L Pereira and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientifica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Scientifica · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Dhrubo Ahmed KhanDepartment of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, just.edu.bd.ORCID https://orcid.org/0000-0002-2027-6173
Mohammad Ashik SheikhDepartment of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, just.edu.bd.
Raihan Rahman ImonDepartment of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, just.edu.bd.
Md ImtiazDepartment of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, just.edu.bd.
Shamin AhmedDepartment of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, just.edu.bd.
Harasit GharamiDepartment of Pharmacy, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, just.edu.bd.
Ryan V LabanaCenter for Health Sciences, Research Institute for Science and Technology, Polytechnic University of the Philippines, Sta. Mesa, Manila, 1008, Philippines, pup.edu.ph.ORCID https://orcid.org/0000-0002-7158-343X
Tajudeen O JimohDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA, mountsinai.org.
Anand GauravDepartment of Pharmaceutical Sciences, School of Health Sciences and Technology, UPES, Dehradun, 248007, Uttarakhand, India, upes.ac.in.
Maria L PereiraDepartment of Medical Sciences & CICECO-Aveiro Institute of Materials, University of Aveiro, Aveiro, Portugal, ua.pt.
Muhammad NawazDepartment of Nano-Medicine Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia, iau.edu.sa.
Julieta Z DungcaSchool of Science and Technology, Centro Escolar University, 9 Mendiola St. San Miguel, Manila, 1005, Philippines.
Md Nazmul HasanDepartment of Genetic Engineering and Biotechnology, Faculty of Biological Science and Technology, Jashore University of Science and Technology, Jashore, 7408, Bangladesh, just.edu.bd.ORCID https://orcid.org/0000-0002-9122-1129
Manik GhoshDepartment of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi, 835 215, Jharkhand, India, bitmesra.ac.in.ORCID https://orcid.org/0000-0003-2846-2971
Veeranoot NissapatornSchool of Allied Health Sciences and World Union for Herbal Drug Discovery (WUHeDD), Walailak University, Nakhon Si Thammarat, Thailand, wu.ac.th.ORCID https://orcid.org/0000-0001-8652-7556

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The papain-like protease (PLpro) of SARS-CoV-2 plays fundamental roles in its replication, and its mechanistic inhibition can impede the virus's replication and infection. Most Plpro inhibitors identified thus far are chemically synthesized and subject to numerous restrictions regarding stability and adverse side effects. Nevertheless, the inhibitors of those compounds can be replaced with natural, selective PLpro inhibitors that are highly stable and have minimal adverse effects. Since ancient times, extracts of

Identifiers

PMID42064585
PMCPMC13127693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.