ArticleExploratory research in clinical and social pharmacy2026
A cross-sectional study of the influence of patient experience and psychological contract on medication adherence in depressive patients.
Article in Exploratory research in clinical and social pharmacy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Effective antidepressant treatment is one of the most important approaches for alleviating depressive symptoms and reducing the risk of suicide. Nevertheless, the high rates of relapse and disability associated with depression are largely due to patients' poor medication adherence. This study investigated the influence of patient experience and psychological contract on medication adherence of outpatients with depression and sought to identify critical factors that could improve medication adherence and provide effective recommendations for the healthcare system. Patients and methods: A cross-sectional survey was conducted in Psychiatric Out-patient department of a tertiary general hospital. A total of 348 participants diagnosed with depression were surveyed by SERVQUAL scale, Psychological Contract Scale and Morisky Scale to assess patient experience, psychological contract and medication adherence, respectively. Results: The mean scores of patient experience, psychological contract, and medication adherence were 7.12 ± 1.25, 3.93 ± 0.36, and 5.32 ± 2.41, respectively. Patient experience and its five dimensions were positively correlated with medication adherence ( Conclusions: Patient experience was positively associated with medication adherence among individuals with depression. Moreover, psychological contract exerted an indirect effect on medication adherence by influencing the quality of the patient experience. These findings highlight the importance of enhancing patient-centered service and fostering trust-based relationships to improve treatment adherence in depressive populations.
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