Deep brain stimulation in

Hiroyuki Sumikura, Naoki Tani, Hiroyo Yoshino, Nobutaka Hattori, Manabu Sakaguchi

Abstract readLetter

In one paragraph

Article in Clinical parkinsonism & related disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hiroyuki SumikuraDepartment of Neurology, Osaka General Medical Center, 3-1-56 Bandai-higashi, Sumiyoshi-ku, Osaka city 558-8558, Osaka, Japan.

Naoki TaniDepartment of Neurosurgery, The University of Osaka, 2-2 Yamadaoka, Suita 565-0871, Osaka, Japan.

Hiroyo YoshinoResearch Institute for Diseases of Old Age, Graduate School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.

Nobutaka HattoriDepartment of Neurology, Faculty of Medicine, Juntendo University, 3-1-3 Hongo, Bunkyo-ku, Tokyo 113-8431, Japan.

Manabu SakaguchiDepartment of Neurology, Osaka General Medical Center, 3-1-56 Bandai-higashi, Sumiyoshi-ku, Osaka city 558-8558, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•VPS13C parkinsonism showed initial STN-DBS benefit then rapid decline.•Motor, cognitive, and psychiatric deterioration occurred after DBS.•Cardiac MIBG converted from normal uptake to denervation over 7 years.•Findings support genetic testing before DBS in early-onset PD.•Surgicogenomics may guide DBS candidate selection in genetic PD.

Indexed as

Autonomic denervationDeep brain stimulationEarly-onset parkinsonismgenetic Parkinson diseaseMIBG scintigraphySurgicogenomicsVPS13C

Identifiers

PMID42064264

DOI10.1016/j.prdoa.2026.100445

PMCPMC13126465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.