Evidence map›Paper›PMID 42064247›Full record

ArticleFrontiers in surgery2026

Medial closing wedge distal femoral osteotomy with patient-specific instrumentation: surgical technique, accuracy, and preliminary outcomes.

Leonardo Puddu, Giovanni Lugani, Francesco Perusi, Hansheng Deng, Tianfeng Zhu, Francesco Pisanu, Edoardo Fantinato, Stefano Pescia, Andrea Fabio Manunta, Carlo Doria and 2 more

Abstract read
In one paragraph

Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Leonardo PudduDepartment of Orthopaedics and Traumatology, ASUIT Rovereto, Rovereto, Italy.
Giovanni LuganiDepartment of Orthopaedics and Traumatology, ASUIT Rovereto, Rovereto, Italy.
Francesco PerusiDepartment of Orthopaedics and Traumatology, ASUIT Rovereto, Rovereto, Italy.
Hansheng DengDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
Tianfeng ZhuDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
Francesco PisanuOrthopedic and Traumatology Unit, Azienda Ospedaliero-Universitaria di Sassari, Sassari, Italy.
Edoardo FantinatoDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
Stefano PesciaDepartment of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Andrea Fabio ManuntaOrthopedic and Traumatology Unit, Azienda Ospedaliero-Universitaria di Sassari, Sassari, Italy.
Carlo DoriaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
Fabrizio CorteseDepartment of Orthopaedics and Traumatology, ASUIT Rovereto, Rovereto, Italy.
Gianfilippo CaggiariDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and aim: Medial closing wedge distal femoral osteotomy (MCW-DFO) is a surgical technique used to treat symptomatic valgus knee deformity. This retrospective study aims to evaluate the reliability of Patient-Specific Instrumentation (PSI) in reproducing preoperative planning and to assess preliminary clinical and radiographic outcomes in patients treated with MCW-DFO using the PSI technique compared to conventional instrumentation. This research was conducted within the framework of the Italian National Recovery and Resilience Plan (PNRR), Mission 6-Health, as part of the PNRR-MAD-2022-12375978-PEARL Project, supporting the development of precision-based surgical strategies to prevent early osteoarthritis progression. Materials and methods: Between 2012 and 2023, 34 patients underwent MCW-DFO, of whom 16 were treated with NewClip Technics PSI and met the study's inclusion and exclusion criteria. Preoperative planning was performed using TraumaCad® software, identifying preoperative and planned mechanical femorotibial angle (mFTA) and mechanical lateral distal femoral angle (mLDFA) values. Postoperative measurements were obtained to determine the difference between planned and achieved alignment as an index of surgical reproducibility. Results: The difference between planned and postoperative values for mFTA and mLDFA angles differed significantly between the two groups. In the PSI group, mean postoperative values differed from planned values by 0.46° for mFTA and 0.66° for mLDFA. In contrast, in the conventional instrumentation group, the difference exceeded 2° for both angles. Conclusions: The PSI technique proved to be significantly more reliable than traditional instrumentation in adhering to preoperative planning in MCW-DFO. The integration of patient-specific technologies represents a precision-surgery approach consistent with PNRR objectives, potentially improving alignment accuracy and contributing to joint preservation strategies in patients at risk of early osteoarthritis.

Indexed as

closing wedgeknee deformitymalalignmentmeniscopathyosteoarthritisosteotomy

Identifiers

PMID42064247
PMCPMC13125120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.