Evidence map›Paper›PMID 42064205›Full record

ReviewResearch and practice in thrombosis and haemostasis2026

Markers for platelet function testing by flow cytometry: where are we now? A clinical perspective.

Benjamin E J Spurgeon

Abstract readReview
In one paragraph

Review in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Special Issue "Flow Cytometry: Applications and Challenges".International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Benjamin E J SpurgeonVersiti Blood Health, Milwaukee, Wisconsin, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flow cytometry is transforming platelet function testing by offering high sensitivity, low sample requirements, and compatibility with thrombocytopenic and pediatric specimens. In contrast to light transmission aggregometry, it enables multiparameter analysis in whole blood, allowing detailed characterization of platelet activation, secretion, and procoagulant function. Current evidence indicates that a carefully selected panel of validated markers provides the most clinically actionable information for diagnosis and patient management. When integrated with clinical context, complementary laboratory data, and reproducible assay design, these readouts offer a pathway toward more accessible, practical, and widely implementable platelet testing, bridging the gap between specialized research assays and standard clinical practice.

Indexed as

Blood Platelet DisordersBlood PlateletsFlow CytometryPlatelet Function TestsBiomarkersHumansPlatelet ActivationPlatelet AggregationPredictive Value of TestsReproducibility of ResultsThrombocytopeniaBiomarkersblood plateletsflow cytometryplatelet activationplatelet function teststhrombocytopenia

Identifiers

PMID42064205
PMCPMC13127191

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.