Evidence map›Paper›PMID 42063977›Full record

ArticleOpen forum infectious diseases2026

Syphilis Diagnosis and Interest in Doxycycline Postexposure Prophylaxis Among Young Black Sexual and Gender Minorities.

E Remund Wiger, E Almirol, M C Castro, J Knox, Y T Chen, A Hazra, D T Duncan, J A Schneider, I Matthews, J Pagkas-Bather

Abstract read
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In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

E Remund WigerChicago Center for HIV Elimination, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-7593-3022
E AlmirolChicago Center for HIV Elimination, University of Chicago, Chicago, Illinois, USA.
M C CastroChicago Center for HIV Elimination, University of Chicago, Chicago, Illinois, USA.
J KnoxDepartment of Epidemiology, Columbia University, Mailman School of Public Health, NewYork, New York, USA.ORCID https://orcid.org/0000-0001-6771-8138
Y T ChenEdward J. Bloustein School of Planning and Public Policy, Rutgers University, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0000-0002-3422-4622
A HazraDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
D T DuncanDepartment of Epidemiology, Columbia University, Mailman School of Public Health, NewYork, New York, USA.
J A SchneiderChicago Center for HIV Elimination, University of Chicago, Chicago, Illinois, USA.
I MatthewsChicago Center for HIV Elimination, University of Chicago, Chicago, Illinois, USA.
J Pagkas-BatherDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-1003-3995

Funding

Survey CoreU2CDA050098 · NIDA · UNIVERSITY OF CHICAGO · PI POLLACK, HAROLD ALEXANDER, SCHNEIDER, JOHN · 2019 to 2019
$17.2M
Characterizing Sleep, ART Adherence and Viral Suppression Among Black Sexual Minority MenR01HL160325 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DUNCAN, DUSTIN T, SCHNEIDER, JOHN · 2021 to 2025
$3.9M
Cannabis use, PrEP and HIV transmission risk Among Black MSM in ChicagoR01DA054553 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DUNCAN, DUSTIN T, KNOX, JUSTIN · 2021 to 2025
$3.6M
NHLBI NIH HHS R01 HL160325NIDA NIH HHS R01 DA054553NIDA NIH HHS U2C DA050098
6 · The paper itself

Abstract

Background: Doxycycline postexposure prophylaxis (doxy-PEP) is a low-cost, effective strategy for preventing syphilis and other bacterial sexually transmitted infections among men who have sex with men and transgender women, yet doxy-PEP remains underused by young black sexual and gender minorities (YBSGM). This analysis examined sociodemographic, sexual health, and substance use factors associated with interest in doxy-PEP among a human immunodeficiency virus (HIV) status-neutral cohort of YBSGM. Methods: The Neighborhoods and Networks Phase 2 (N2P2) cohort included YBSGM, and our primary outcome was interest in doxy-PEP. Generalized linear models were fit to calculate the unadjusted and adjusted relative risks (RRs) between interest in doxy-PEP and sociodemographic and health factors. Results: A total of 538 participants were included in the analysis, with 59.9% reporting interest in doxy-PEP. Participants interested in doxy-PEP were older (RR, 1.02 [95% confidence interval (CI), 1.00-1.04]; Conclusions: YBSGM who were interested in doxy-PEP were more likely to have had a syphilis diagnosis and participate in group sex. YBSGM with these risk factors represent an important demographic for the scale-up of doxy-PEP use.

Indexed as

HIVsubstance usesyphilisYBSGM

Identifiers

PMID42063977
PMCPMC13126516

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.