Evidence map›Paper›PMID 42063839›Full record

ArticleJACS Au2026

Paranemic Cohesion of DNA under Isothermal Conditions.

Lauren A Anderson, Akul Patel, Bharath Raj Madhanagopal, Hannah Talbot, Nada Kabbara, Ken Halvorsen, Arun Richard Chandrasekaran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren A AndersonDepartment of Nanoscale Science and Engineering, University at Albany, State University of New York, Albany, New York 12222, United States.
Akul PatelDepartment of Nanoscale Science and Engineering, University at Albany, State University of New York, Albany, New York 12222, United States.
Bharath Raj MadhanagopalDepartment of Nanoscale Science and Engineering, University at Albany, State University of New York, Albany, New York 12222, United States.ORCID https://orcid.org/0000-0003-1043-8754
Hannah TalbotDepartment of Nanoscale Science and Engineering, University at Albany, State University of New York, Albany, New York 12222, United States.
Nada KabbaraDepartment of Nanoscale Science and Engineering, University at Albany, State University of New York, Albany, New York 12222, United States.
Ken HalvorsenThe RNA Institute, University at Albany, State University of New York, Albany, New York 12222, United States.ORCID https://orcid.org/0000-0002-2578-1339
Arun Richard ChandrasekaranDepartment of Nanoscale Science and Engineering, University at Albany, State University of New York, Albany, New York 12222, United States.ORCID https://orcid.org/0000-0001-6757-5464

Funding

Manipulating nucleic acids: applications in RNA biosensing, single-molecule analysis, and DNA nanotechnologyR35GM124720 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI Ken A Halvorsen · 2017 to 2026
$4.6M
Programmable DNA Nanostructures as Biomedical and Structural ScaffoldsR35GM150672 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI Arun Richard Chandrasekaran · 2023 to 2026
$1.7M
NIGMS NIH HHS R35 GM124720NIGMS NIH HHS R35 GM150672
6 · The paper itself

Abstract

Recent progress in DNA nanotechnology has shown the isothermal assembly of several DNA nanostructures. Isothermal assembly allows DNA nanostructure construction in a variety of ions while simplifying DNA nanotechnology by avoiding the need for thermal cyclers and expands utility by enabling attachment of guest biomolecules on DNA nanostructures at ambient or physiological temperatures. The paranemic crossover (PX) DNA motif has been used in the construction of DNA nanostructures, paranemic cohesion has been used to connect DNA structures as an alternate to sticky end cohesion, and PX DNA has also been implied to have a biological role in homology recognition. In that context, here we demonstrate the successful isothermal assembly of the PX DNA motif in magnesium (Mg

Indexed as

counterionsDNA nanostructuresDNA nanotechnologyisothermal assemblyparanemic crossover DNAPX DNA

Identifiers

PMID42063839
PMCPMC13126193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.