Evidence map›Paper›PMID 42063790›Full record

ArticleFrontiers in medicine2026

Capillaroscopic patterns are associated with interstitial lung disease, skin fibrosis, anti-Th/To antibodies and quality of life in systemic sclerosis: a prospective cross-sectional study.

Jakub Trefler, Anna Pasierb, Lidia Lech, Hubert Czaplicki, Katarzyna Życińska

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jakub TreflerDepartment of Rheumatology, Connective Tissue Diseases and Rare Diseases, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.
Anna PasierbDepartment of Rheumatology, Connective Tissue Diseases and Rare Diseases, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.
Lidia LechDepartment of Rheumatology, Connective Tissue Diseases and Rare Diseases, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.
Hubert CzaplickiDepartment of Rheumatology, Connective Tissue Diseases and Rare Diseases, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.
Katarzyna ŻycińskaDepartment of Rheumatology, Connective Tissue Diseases and Rare Diseases, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Capillaroscopic patterns in systemic sclerosis (SSc) are routinely assessed by nailfold videocapillaroscopy (NVC), yet their broader clinical relevance remains incompletely defined. Methods: In a prospective cross-sectional study of 70 SSc patients, we evaluated associations between NVC patterns and key clinical domains: interstitial lung disease (ILD), skin fibrosis (the modified Rodnan Skin Score, mRSS), SSc-specific autoantibody profile including anti-Th/To, immunosuppressive treatments, and patient-reported outcome measures (PROMs): SSc Quality of Life scale (SScQoL), Health Assessment Questionnaire-Disability Index (HAQ-DI), and Visual Analog Scales (VAS) for pain and disease activity (PtGA). Statistical methods included Spearman correlation, Mann-Whitney Results: Advanced NVC patterns (4-5) were significantly associated with ILD ( Conclusion: Our study demonstrates significant associations between NVC severity and selected clinical, serological, therapeutic, and patient-reported domains in SSc.

Indexed as

biomarkerscapillaroscopyinterstitial lung diseasepatient-reported outcome measuressystemic sclerosis

Identifiers

PMID42063790
PMCPMC13124522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.