Evidence map›Paper›PMID 42063749›Full record

ArticlePlastic and reconstructive surgery. Global open2026

Factors Associated With Venous Complications in Lower Extremity Free Flap Reconstruction: A Multivariate Analysis.

Bora Kahramangil, Ellen Wang, Imran Rizvi, Jessica R Nye, Kylie Swiekatowski, Alexandra Dunker, Kate Liao, Michael H Haydon, Jeffrey G Trost, Mohin A Bhadkamkar

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bora KahramangilFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Ellen WangFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Imran RizviFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Jessica R NyeFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Kylie SwiekatowskiFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Alexandra DunkerFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Kate LiaoFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Michael H HaydonFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Jeffrey G TrostFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.
Mohin A BhadkamkarFrom the Division of Plastic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Due to their dependent location, lower extremity (LE) free flaps (FFs) are at increased risk for venous complications. This study analyzes risk factors of venous complications in LE FFs. Methods: A single-center retrospective review was conducted of adult patients undergoing LE FF reconstruction from 2016 to 2025. Variables included demographics, wound and operative characteristics, and the number of venous anastomoses. The primary outcome was venous complications, defined as a composite variable encompassing venous congestion, flap loss due to venous causes, and flap hematoma. Results: The cohort consisted of 370 patients undergoing LE FF reconstructions. Single venous anastomosis was used in 123 (33.2%) patients, and dual venous anastomoses were used in 247 (66.8%). The overall venous complication rate was 7.3%. In the multivariate model, the only independent predictor for venous complication was the use of the superficial venous system as the sole drainage route (odds ratio, 14.5; Conclusions: Compared with anastomoses to deep veins, the use of the superficial venous system as the sole venous drainage may lead to an increased risk of venous complications. On the other hand, routine performance of a second venous anastomosis does not decrease the risk of venous congestion. It may be safe to use veins within the zone of injury when necessary.

Identifiers

PMID42063749
PMCPMC13124393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.