ArticleFrontiers in oncology2026
Synchronous gastric and appendiceal mucinous adenocarcinomas: a rare case report.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Pleural Pseudomyxoma Secondary to Appendiceal Mucinous Adenocarcinoma: A Case Report.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gastric mucinous adenocarcinoma (GMA) and appendiceal mucinous adenocarcinoma (AMA) are rare neoplasms that frequently present at advanced stages characterized by peritoneal dissemination. The simultaneous occurrence of these two malignancies is exceedingly uncommon. Case presentation: A 66-year-old man presented with abdominal discomfort and was initially diagnosed with gastric adenocarcinoma based on endoscopic biopsy findings. Computed tomography imaging revealed the presence of ascites and peritoneal nodules. Following neoadjuvant chemoimmunotherapy comprising XELOX and sintilimab, diagnostic laparoscopy identified a concurrent AMA accompanied by pseudomyxoma peritonei (PMP). Subsequently, the patient underwent radical gastrectomy, appendectomy, and hyperthermic intraperitoneal chemotherapy (HIPEC). Histopathological examination confirmed the synchronous presence of GMA and AMA. Importantly, serial molecular analyses demonstrated a treatment-induced transition from mismatch repair-deficient (dMMR)/microsatellite instability-high (MSI-H) status to mismatch repair-proficient (pMMR) status. Conclusion: This rare case highlights the critical importance of comprehensive preoperative imaging and meticulous surgical evaluation in the diagnosis of uncommon synchronous malignancies. Furthermore, the observed alteration in molecular phenotype following chemoimmunotherapy suggests that such treatment modalities may influence tumor biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.