Evidence map›Paper›PMID 42063620›Full record

ReviewQRB discovery2026

Mass spectrometry integrates protein design into structural biology method development.

Alexander Stevens, Hannah Osterholz, Vsevolod Viliuga, Thibault Vosselman, Surabhi Kokane, Erik G Marklund, Arne Elofsson, Axel Leppert, Michael Landreh

Abstract readReview
In one paragraph

Review in QRB discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander StevensDepartment of Cell and Molecular Biology, Uppsala University, Sweden.
Hannah OsterholzDepartment of Cell and Molecular Biology, Uppsala University, Sweden.
Vsevolod ViliugaScience for Life Laboratory and the Department of Biochemistry and Biophysics, Stockholm University, Sweden.
Thibault VosselmanDepartment of Cell and Molecular Biology, Uppsala University, Sweden.
Surabhi KokaneDepartment of Cell and Molecular Biology, Uppsala University, Sweden.
Erik G MarklundDepartment of Chemistry for Life Sciences, Uppsala University, Sweden.
Arne ElofssonScience for Life Laboratory and the Department of Biochemistry and Biophysics, Stockholm University, Sweden.
Axel LeppertDepartment of Cell and Molecular Biology, Uppsala University, Sweden.
Michael LandrehDepartment of Cell and Molecular Biology, Uppsala University, Sweden.ORCID https://orcid.org/0000-0002-7958-4074

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in machine learning (ML) have transformed protein science, enabling engineering and

Indexed as

biophysical methodsion mobility mass spectrometrymachine learningprotein structure analysisstructure prediction

Identifiers

PMID42063620
PMCPMC13125771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.