Evidence map›Paper›PMID 42063588›Full record

ReviewBJUI compass2026

Lymph node dissection during cystectomy for non-muscle-invasive bladder cancer: A systematic review.

Sean Lim, Lucielle Standish, Harrison Liu, Eldho Paul, Weranja Ranasinghe

Abstract readReview
In one paragraph

Review in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sean LimDepartment of Urology Monash Health Berwick Australia.ORCID https://orcid.org/0000-0002-5921-9643
Lucielle StandishDepartment of Urology Monash Health Berwick Australia.
Harrison LiuDepartment of Medicine, Nursing & Health Sciences Monash University Berwick Australia.
Eldho PaulMonash Centre for Health Research and Implementation Monash University Berwick Australia.
Weranja RanasingheDepartment of Urology Monash Health Berwick Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Radical cystectomy (RC) is standard for muscle-invasive disease (MIBC) and utilised frequently in high-risk non-muscle-invasive bladder cancer (NMIBC). Pelvic lymph node dissection (PLND) is routinely performed during RC for MIBC, demonstrating a survival benefit. However, the oncologic value in NMIBC remains uncertain. As such, a systematic review was conducted to determine whether PLND confers an oncologic benefit in NMIBC patients undergoing RC. Materials and methods: A systematic search of MEDLINE, Embase and PubMed (January 1989-January 2025) was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines (CRD42023443011). Eligible studies included NMIBC patients undergoing RC with or without PLND. Data extraction and quality assessment (ROBINS-I, MINORS) were performed independently by two reviewers. Results: Twenty-one retrospective studies ( Conclusions: PLND appears to improve staging and survival in high-risk NMIBC, especially pT1 disease. Routine PLND for low-risk Ta/Tis disease is unsupported. Standardised definitions of PLND extent and prospective evaluation are needed to confirm its therapeutic role.

Indexed as

bladder cancercystectomylymph node dissectionnon‐muscle‐invasive bladder cancersurvival outcomessystematic review

Identifiers

PMID42063588
PMCPMC13124444

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.