Evidence map›Paper›PMID 42063450›Full record

ArticleProceedings (Baylor University. Medical Center)

Temporal trends in the incidence, mortality, and prevalence of gallbladder and biliary diseases in high-income countries compared to the USA, 1990 to 2021.

Muhammad Ahmad Nadeem, Anna J Willingham, Mudasar Nisar, Abdul Rafeh Awan, Fatima Ashfaq, Hamza Ashraf, Rabia Javed, Mohammed A Quazi, Jibran Ikram, Asad Ullah and 2 more

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Article in Proceedings (Baylor University. Medical Center). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Muhammad Ahmad NadeemDepartment of Liver Transplant Surgery, Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Anna J WillinghamDepartment of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Mudasar NisarDepartment of Medicine, Services Institute of Medical Sciences, Lahore, Pakistan.
Abdul Rafeh AwanDepartment of Medicine, Nishtar Medical University, Multan, Pakistan.ORCID https://orcid.org/0000-0002-6411-8759
Fatima AshfaqDepartment of Medicine, Nishtar Medical University, Multan, Pakistan.
Hamza AshrafDepartment of Medicine, Allama Iqbal Medical College, Lahore, Pakistan.
Rabia JavedDepartment of Medicine, Services Institute of Medical Sciences, Lahore, Pakistan.
Mohammed A QuaziDepartment of Family and Community Health, West Virginia University, Morgantown, West Virginia, USA.
Jibran IkramDepartment of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA.
Asad UllahDepartment of Pathology, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Abu Baker SheikhDepartment of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Amir Humza SohailDepartment of Surgical Oncology, University of New Mexico, Albuquerque, New Mexico, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gallbladder and biliary diseases remain major global health concerns, with trends shaped by lifestyle, metabolic risk factors, and healthcare access. This study evaluated long-term changes in age-standardized incidence (ASIR), prevalence (ASPR), and mortality (ASMR) in high-Social Demographic Index (SDI) countries and the United States from 1990 to 2021. Methods: Data were obtained from the Global Burden of Disease 2021 database. ASIR, ASPR, and ASMR were extracted for both regions. Joinpoint regression analysis generated annual percentage changes with 95% confidence intervals to identify significant temporal shifts. Results: In high-SDI countries, males showed declines in ASMR (2.03 to 1.67), ASPR (3210.0 to 2962.4), and ASIR (987.4 to 932.0) per 100,000. Females showed similar reductions: ASMR 1.79 to 1.34, ASPR 5141.8 to 4352.3, and ASIR 1912.0 to 1706.7. In the US, ASMR, ASPR, and ASIR decreased from 1.57 to 1.29, 2495.8 to 2278.2, and 757.5 to 716.0 in males, and from 1.17 to 0.96, 4921.6 to 3796.5, and 1856.5 to 1519.4 in females. Discussion: Mortality and prevalence declined in both regions, while incidence showed modest reductions. The persistently higher US burden likely reflects obesity, metabolic disease, and healthcare disparities, emphasizing the need for targeted prevention and equitable access to care.

Indexed as

Gallbladder and biliary diseaseGlobal Burden of Diseaseincidencemortalityprevalence

Identifiers

PMID42063450
PMCPMC13128021

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.