Observational studyJournal of cardiothoracic surgery2026
Feasibility and postoperative analgesic profile of multimodal analgesia including combined serratus anterior plane block in minimally invasive cardiac surgery: a prospective observational study.
Observational study in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06326320 (The Effects of Combined Serratus Anterior Plane Block on Postoperative Acute Pain After Minimally Invasive Cardiac Surgery), which is not on this map. Not yet cited in PubMed.
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The Effects of Combined Serratus Anterior Plane Block on Postoperative Acute Pain After Minimally Invasive Cardiac Surgery
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10 authors.
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Abstract
backgroundAlthough minimally invasive cardiac surgery (MICS) is less invasive, patients may still experience significant postoperative pain. This observational study aimed to evaluate the feasibility and postoperative analgesic profile associated with the combined serratus anterior plane block (CSAPB), a component of multimodal analgesia in patients undergoing MICS.
methodsTwenty patients, aged 18 to 80, who underwent MICS and provided written informed consent, were included in the study. Standard cardiac anesthesia monitoring was performed. Ultrasound-guided CSAPB was performed preemptively after induction of general anesthesia as part of a multimodal analgesia strategy, using a total of 40 mL of 0.25% bupivacaine, with 20 mL administered into each of the deep and superficial serratus anterior planes. All patients received intravenous acetaminophen 1 g and tramadol 1 mg·kg
resultsThe hemodynamic parameters remained within clinically acceptable ranges. In 2 patients (10%), VAS scores exceeded 40 mm, requiring rescue analgesia. A statistically significant difference was observed in terms of changes in rest VAS scores (p = 0.015). Significant differences were also observed in the changes in cough VAS scores over time (p = 0.003). Nausea and vomiting were observed in 2 patients (10%). No other complications were observed during the follow-up period.
conclusionsMultimodal analgesia, including CSAPB, appears to be a feasible regional analgesia technique associated with low postoperative pain scores and minimal rescue analgesic requirements in patients undergoing MICS via right mini-thoracotomy.
trial registrationClinicaltrials Registration No: NCT06326320, Registration Date: 17/03/2024.
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