Evidence map›Paper›PMID 42063067›Full record

ReviewJournal of translational medicine2026

Applications and research progress of PET/CT in dynamic monitoring of immunotherapy in melanoma.

Lilu Xie, Dai Shi, Jiayi Huang, Wujian Mao, Shaoluan Zheng, Chuanyuan Wei, Dengfeng Cheng, Jianying Gu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lilu Xie *Department of Plastic Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China.
Dai Shi *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Jiayi Huang *Department of Plastic Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China.
Wujian MaoDepartment of Nuclear Medicine, Shanghai Clinical Research and Trial Center, 1599 Keyuan Road, Shanghai, China.
Shaoluan ZhengXiamen Clinical Research Center for Cancer Therapy, Xiamen, China.
Chuanyuan WeiDepartment of Plastic Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China. wei.chuanyuan@zs-hospital.sh.cn.
Dengfeng ChengDepartment of Nuclear Medicine, Shanghai Clinical Research and Trial Center, 1599 Keyuan Road, Shanghai, China. chengdf@shanghaitech.edu.cn.
Jianying GuDepartment of Plastic Surgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China. prof_jianyinggu@163.com.

Funding

China Postdoctoral Science Foundation 2022M710769, 2022TQ0072National Natural Science Foundation of China 82203528, 81972559, 82272891
6 · The paper itself

Abstract

backgroundMelanoma is a highly aggressive malignancy, and conventional therapies have limited efficacy in metastatic cases. The advent of immune checkpoint inhibitors (ICIs) has significantly improved patient prognosis. However, challenges such as heterogeneous responses, resistance, and immune-related adverse events (irAEs) necessitate reliable tools for early efficacy prediction and dynamic assessment. MAIN BODY: As a molecular imaging modality that integrates structural and functional information, Positron Emission Tomography/Computed Tomography (PET/CT)-particularly through

conclusionsPET/CT represents a valuable imaging modality for comprehensive assessment of immunotherapy in melanoma. With continued refinement of response criteria and the development of immune-targeted tracers, PET-based imaging is expected to further facilitate personalized and dynamic immunotherapy strategies.

Indexed as

ImmunotherapyMelanomaPositron Emission Tomography Computed TomographyAnimalsHumansImmunotherapyMelanomaPET/CTResponse evaluation

Identifiers

PMID42063067
PMCPMC13288796

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.