Evidence map›Paper›PMID 42062956›Full record

SynthesisBMC ophthalmology2026

Effect of anterior chamber air tamponade after phacoemulsification cataract surgery: a systematic review and meta-analysis.

Xiangbin Guan, Qian Luo, Furong Liao, Li Jiang, Lei Yang, Jingyi Zhu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiangbin GuanMedical College, Wuhan University of Science and Technology, Wuhan, 430065, Hubei Province, China.
Qian LuoMedical College, Wuhan University of Science and Technology, Wuhan, 430065, Hubei Province, China.
Furong LiaoDepartment of Ophthalmology, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, 430000, Hubei Province, China.
Li JiangDepartment of Ophthalmology, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, 430000, Hubei Province, China.
Lei YangDepartment of Ophthalmology, General Hospital of Central Theater Command of People's Liberation Army, Wuhan, 430000, Hubei Province, China. shitouyang@126.com.
Jingyi ZhuMedical College, Wuhan University of Science and Technology, Wuhan, 430065, Hubei Province, China. dr.zhujingyi@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the safety of anterior chamber air tamponade post-phacoemulsification on the cornea compared to balanced salt solution or Ringer's lactate filling, and summarize its potential influence on the aspects like the risk of postoperative endophthalmitis and Descemet's membrane detachment (DMD).

methodsThis meta-analysis was conducted using Review Manager 5.4 and included studies that evaluated post-phacoemulsification air tamponade compared with no air tamponade before October 2025. Methodological quality was assessed using the Cochrane Risk of Bias tool. This review was registered in PROSPERO (CRD420251177446) and followed PRISMA guidelines.

resultsAmong seven included studies (1340 eyes), there were no significant between-group differences (mean difference [95% confidence interval]) at 1 month, with or without air tamponade, in the endothelial cell density (-103.59 [-256.86 to 49.68] cells/mm

conclusionsIntracameral air injection demonstrated comparable short-term corneal endothelial safety, with the potential added benefits of reduced inflammation and infection risk and of protection of the Descemet's membrane.

trial registrationPROSPERO, CRD420251177446. Registered 2025. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

AirAnterior ChamberEndotamponadePhacoemulsificationPostoperative ComplicationsEndophthalmitisHumansIntracameral InjectionAnterior chamber air tamponadeCataractCorneal endotheliumPhacoemulsification

Identifiers

PMID42062956
PMCPMC13281649

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.