Evidence map›Paper›PMID 42062939›Full record

ArticleBMC infectious diseases2026

Distribution of lactic acid bacteria in vaginal samples from Cameroonian women.

Prisca Clemence Waita Vilidina, Serge Damase Oyong Assiene, Francky Steve Nodem Sohanang, Rodrigue Louis Messina Ngah, Marcelle Abanda, Carole Else Eboumbou Moukoko, Guy Pascal Ngaba, Dieudonné Adiogo

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Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Prisca Clemence Waita VilidinaFaculty of Medicine and Pharmaceutical Sciences (FMPS), University of Douala, P.O. Box 2701, Douala, Cameroon. waitavildina@gmail.com.
Serge Damase Oyong AssieneFaculty of Medicine and Pharmaceutical Sciences (FMPS), University of Douala, P.O. Box 2701, Douala, Cameroon.
Francky Steve Nodem SohanangDepartment of Food Engineering and Quality Control, University of Ngaoundéré, P.O. Box 455, Ngaoundéré, Cameroon.
Rodrigue Louis Messina NgahFaculty of Science, University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon.
Marcelle AbandaPasteur Centre of Cameroon, P.O. Box 1274, Yaoundé, Cameroon.
Carole Else Eboumbou MoukokoFaculty of Medicine and Pharmaceutical Sciences (FMPS), University of Douala, P.O. Box 2701, Douala, Cameroon.
Guy Pascal NgabaFaculty of Medicine and Pharmaceutical Sciences (FMPS), University of Douala, P.O. Box 2701, Douala, Cameroon.
Dieudonné AdiogoFaculty of Medicine and Pharmaceutical Sciences (FMPS), University of Douala, P.O. Box 2701, Douala, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous bacteria coexist in the human body and constitute the 'normal microbiota'. Data on the normal vaginal microbiota are limited in Africa, particularly in Cameroon. This study aimed to determine the distribution of lactic acid bacteria (LAB) isolated from vaginal samples of Cameroonian women.

methodsThis cross-sectional analytical study was conducted in Douala, Cameroon, from March 2024 to March 2025. It included non-menopausal women aged 18 to 50 years without gynaecological infections. Vaginal swabs were cultured on MRS and M17 media and identified by MALDI-TOF mass spectrometry at the Pasteur Centre for lactic acid bacteria, and by API mini-galleries for pathogenic organisms. Microbiota typing was performed using the Nugent scoring system. Descriptive and inferential statistics were conducted using SPSS v25.0, XLSTAT, and the VITEK MS Knowledge Base. Logistic regression and Poisson regression were applied where appropriate; significance was set at p < 0.05.

resultsA total of 783 participants were enrolled; the majority were aged 29-39 years (44.2%). Microbiota type IV (depleted) was the most prevalent (48.1%). Overall, 67.6% of samples harboured pathogenic bacteria, while 32.4% yielded LAB. Among 260 LAB isolates, Enterococcus spp. dominated (59.2%), mainly E. faecalis (33.5%) and E. faecium (22.3%). Bacteria belonging to the former Lactobacillus group accounted for only 18.8% of all LAB. Age (p = 0.019), region of origin (p = 0.012), and marital status (p = 0.011) were significantly associated with LAB prevalence.

conclusionThe distribution of vaginal lactic acid bacteria in Cameroonian women depends on age, marital status, and region of origin. The predominance of Enterococcus spp. over canonical lactobacilli represents a distinctive microbiological signature, potentially reflecting biogeographical and socio-cultural adaptations, which calls for region-specific approaches to vaginal health management.

Indexed as

LactobacillalesVaginaAdolescentAdultCameroonCross-Sectional StudiesFemaleHumansMicrobiotaMiddle AgedYoung AdultCameroonDoualaLactic acid bacteriaLactobacilliVaginal microbiotaWomen

Identifiers

PMID42062939
PMCPMC13326324

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