Evidence map›Paper›PMID 42062928›Full record

ArticleBMC geriatrics2026

Development and internal validation of a 30-day readmission risk model for older adults using Swiss electronic health record data: a retrospective cohort study.

Laura Maria Steiner, Sandra M G Zwakhalen, Loris Bonetti, Sabine Hahn

Abstract readValidation StudyMulticenter Study
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Laura Maria SteinerNursing Research Competence Centre, Department of Nursing, Ente Ospedaliero Cantonale, Viale Officina 3, Bellinzona, 6500 , Switzerland. lauramaria.steiner@eoc.ch.
Sandra M G ZwakhalenDepartment of Health Services Research, Faculty of Health, Medicine and Life Sciences, CAPHRI School of Public Health and Primary Care, Maastricht University, Maastricht, the Netherlands.
Loris BonettiNursing Research Competence Centre, Department of Nursing, Ente Ospedaliero Cantonale, Viale Officina 3, Bellinzona, 6500 , Switzerland.
Sabine HahnApplied Research & Development in Nursing, Department of Health Professions, Bern University of Applied Sciences, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnplanned 30-day readmissions in discharged older adults often reflect unmet needs and fragmented care transitions. Existing prediction models frequently lack geriatric specificity, clinical interpretability, and applicability to decentralised European healthcare systems. This study aimed to develop a clinically interpretable risk model for older adults using routine discharge data. Findings may provide a basis for targeted interventions.

methodsWe conducted a retrospective cohort study using electronic health record (EHR) data from a Swiss multi-site hospital network. Adults aged ≥ 65 years discharged alive in 2024 were eligible, excluding planned readmission, oncology/palliative cases, in-hospital deaths, and records with missing predictors. Of 15,635 discharges, 12,814 met inclusion criteria. 9,429 (60.3%) were retained for complete-case analysis. A multivariable logistic regression model with backward selection predicted unplanned 30-day readmission. Model performance was evaluated by AUC, calibration, decision curve analysis (DCA), and bootstrap validation, with a Fine-Gray model addressing competing risk of mortality.

resultsAmong 9,429 patients (mean age 78.0 years; 45.5% female), 1,845 (19.6%) had an unplanned 30-day readmission. Independent predictors were polypharmacy (OR 1.83), home care (OR 1.61), male sex (OR 1.42), low fall risk (vs. high; OR 1.41), moderate care intensity (vs. high; OR 1.30), comorbidity count (OR 1.12/diagnosis), younger age (OR 0.99/year), and shorter stay (OR 0.98/day). The model showed an AUC of 0.716 (95% CI 0.706-0.726), but calibration was poor, with risk overestimation at low predicted probabilities. At a 10% threshold, sensitivity was 7.5%, specificity 98.1%, positive predictive value 49.5%, and negative predictive value 81.4%. Compared with LACE index (AUC 0.707, 95% CI 0.694-0.720), performance improved modestly but significantly (p < 0.01).

conclusionsNearly one in five older adults was readmitted within 30 days, underscoring the burden of rehospitalisation and its link to quality-of-care. The model identified clinically relevant, EHR-available predictors, including medical complexity and care dependency. Despite acceptable discrimination, calibration was suboptimal and sensitivity low, limiting immediate clinical application. Future refinement and external validation may enhance utility. This model may provide a pragmatic starting point for risk-stratified discharge planning research and guiding transitional care interventions.

trial registrationStudy protocol was registered on the Open Science Framework (OSF) ( https://osf.io/vkte2/ ; 10 May 2025).

Indexed as

Electronic Health RecordsPatient ReadmissionAgedAged, 80 and overCohort StudiesFemaleHumansMaleRetrospective StudiesRisk AssessmentSwitzerlandDischarge planningElectronic health recordsGeriatric assessmentHospital readmissionLogistic regressionOlder adultsPolypharmacyPrediction modelRisk stratificationTransitional care

Identifiers

PMID42062928
PMCPMC13276931

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.