Evidence map›Paper›PMID 42062667›Full record

ArticleJournal of fluorescence2026

Design, Synthesis, and Characterization of TEPE-Zn-MOF as a Turn-On Fluorescent Probe for Pb²⁺ Detection.

Kinjal Modi, Dhruvi Kher, Bhavesh Dhumale, Nihal Patel, Keyur Bhatt, Chirag N Patel, Vaibhav Bhatt, Mukesh Chaudhari, Hitesh Patel, Hasit Vaghani and 3 more

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Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Kinjal ModiDepartment of Chemistry, Faculty of Science, Ganpat University, Kherva, Mehsana, Gujarat, 384012, India.
Dhruvi KherDepartment of Chemistry, School of Science, Indrashil University, Rajpur, Mehsana, 382740, India.
Bhavesh DhumaleDepartment of Chemistry, Faculty of Science, Ganpat University, Kherva, Mehsana, Gujarat, 384012, India.
Nihal PatelDepartment of Chemistry, Faculty of Science, Ganpat University, Kherva, Mehsana, Gujarat, 384012, India. nihalpatel1610@gmail.com.
Keyur BhattDepartment of Chemistry, Faculty of Science, Ganpat University, Kherva, Mehsana, Gujarat, 384012, India.
Chirag N PatelDrug Design & Development Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, NIH, Baltimore, MD, 21224, USA.
Vaibhav BhattSchool of Applied Science and technology, Gujarat Technological University, Ahmedabad, India.
Mukesh ChaudhariDepartment of Chemistry, School of Sciences, Gujarat University, Ahmedabad, India.
Hitesh PatelDepartment of Chemistry, School of Sciences, Gujarat University, Ahmedabad, India.
Hasit VaghaniDepartment of Chemistry, Faculty of Science, Ganpat University, Kherva, Mehsana, Gujarat, 384012, India. hvv01@ganpatuniversity.ac.in.
Krunal ModiDepartment of Chemistry, School of Science, Indrashil University, Rajpur, Mehsana, 382740, India. kmodi5033@gmail.com.
Sandeep KumarFaculty of Sciences, Chaudhary Ranbir Singh University, Jind, Haryana, 126102, India.
Disha KothariCentre of Excellence in Nutritional Supplements Testing for Sportsperson (CoE-NSTS), National Forensic Sciences University (NFSU), Gandhinagar, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selective detection of Pb²⁺ using fluorescent probes remains formidable. As the most reported sensors suffer from fluorescence quenching and interference from competing metal ions. In order to address this limitation, we synthesized a Zn-based metal–organic framework (TEPE-Zn-MOF) incorporating a π-conjugated tetra(pyridyl)ethene ligand that encourages ligand-centered emission and reachable coordination sites. The resulting framework is structurally robust, crystalline, and thermally stable, which provides an effective platform for fluorescence sensing. TEPE-Zn-MOF reveals strong emission that is largely insensitive to a large range of metal ions. It shows a pronounced turn-on fluorescence enhancement specifically in the presence of Pb²⁺, which is fourfold high in intensity and has a detection limit of 5.1 µM. This selective response is characteristic of chelation-enhanced fluorescence arising from strong Pb²⁺ coordination at pyridyl nitrogen sites, supported by DFT analysis and validated against ICP-MS for real-sample monitoring.

Indexed as

Fluorescent DyesLeadMetal-Organic FrameworksPyridinesZincDensity Functional TheoryFluorescent Chemosensor CompoundsMolecular StructureSpectrometry, FluorescenceFluorescent Chemosensor CompoundsFluorescent DyesLeadMetal-Organic FrameworksPyridinesZincMetal–organic frameworkPb²⁺ detectionTurn-on fluorescenceZinc-based MOF

Identifiers

PMID42062667

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.