Evidence map›Paper›PMID 42062649›Full record

ArticleJournal of natural medicines2026

Piperlongumine A attenuates RANKL-induced osteoclastogenesis by targeting MAPK signaling and downregulating c-Fos and NFATc1.

Tran Thi Thu Phuong, Le Hoang Long, Phan Thi Tu Uyen, Nguyen Xuan Nhiem, Jeong-Hyung Lee, Nguyen Hai Dang

Abstract read
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In one paragraph

Article in Journal of natural medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tran Thi Thu PhuongUniversity of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Nghia Do, 10000, Hanoi, Vietnam.
Le Hoang LongDepartment of Biochemistry, College of Natural Sciences, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, 24341, Gangwon-do, Republic of Korea.
Phan Thi Tu UyenUniversity of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Nghia Do, 10000, Hanoi, Vietnam.
Nguyen Xuan NhiemInstitute of Chemistry, VAST, 18 Hoang Quoc Viet, Nghia Do, 10000, Hanoi, Vietnam.
Jeong-Hyung LeeDepartment of Biochemistry, College of Natural Sciences, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, 24341, Gangwon-do, Republic of Korea. jhlee36@kangwon.ac.kr.
Nguyen Hai DangUniversity of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Nghia Do, 10000, Hanoi, Vietnam. nguyen-hai.dang@usth.edu.vn.

Funding

University of Science and Technology of Hanoi Research Group Phytomed
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

C-FosMAPKsNFATc1OsteoclastogenesisPiperlongumine APiper longum L.

Identifiers

PMID42062649

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.