Evidence map›Paper›PMID 42062541›Full record

ArticleNPJ digital medicine2026

Reinforcement learning improves LLM accuracy and reasoning in disease classification from radiology reports.

Yishu Wei, Yi Lin, Adam Flanders, George Shih, Yifan Peng

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yishu WeiDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Yi LinDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Adam FlandersDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
George ShihDepartment of Radiology, Weill Cornell Medicine, New York, NY, USA.
Yifan PengDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA. yip4002@med.cornell.edu.

Funding

NIBIB NIH HHS 75N920202D00021NSF CAREER Award 2145640
6 · The paper itself

Abstract

Accurate disease classification from radiology reports is essential for many applications. While supervised fine-tuning (SFT) of lightweight LLMs improves accuracy, it can degrade reasoning. We propose a two-stage approach: SFT on disease labels followed by Group Relative Policy Optimization (GRPO) to refine predictions by optimizing accuracy and format without reasoning supervision. Across three radiologist-annotated datasets, SFT outperformed baselines and GRPO further improved classification and enhanced reasoning recall and comprehensiveness.

Identifiers

PMID42062541
PMCPMC13338140

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.