ArticleScientific reports2026
Synthesis and long-term antibacterial performance of nano-montmorillonite-loaded polymyxin B (NMMT@PMB) against Salmonella in an ex vivo study.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Salmonella is a Gram-negative bacterium causing intestinal infections. Polymyxin B (PMB) is an effective antibiotic against Salmonella, but the emergence of antibiotic resistance poses a growing concern. To address this challenge, this study synthesized a new nanocarrier by functionalizing nano-montmorillonite (NMMT) with PMB by adsorption, namely NMMT@PMB. PMB adsorption on NMMT followed the Langmuir isotherm and pseudo‑first‑order kinetics, and its release kinetics followed a diffusion-controlled mechanism. Although the minimum inhibitory concentration (MIC) of NMMT@PMB (2.78 and 44.54 µg/mL) was slightly higher than that of free PMB (2 and 32 µg/mL) for PMB-sensitive (S
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