Evidence map›Paper›PMID 42062426›Full record

ArticleScientific reports2026

Mathematical modeling of immune counter-regulation predicts efficacy of fractionated CD8

Hiroki Kasai, Koji Nagaoka, Artem Lysenko, Kazuhiro Kakimi, Tatsuhiko Tsunoda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hiroki KasaiLaboratory for Medical Science Mathematics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, 113-0033, Japan.
Koji NagaokaDepartment of Immunology, Faculty of Medicine, Kindai University, Sakai, Osaka, 590-0197, Japan.
Artem LysenkoLaboratory for Medical Science Mathematics, Department of Biological Sciences, School of Science, The University of Tokyo, Tokyo, 113-0033, Japan.
Kazuhiro KakimiDepartment of Immunology, Faculty of Medicine, Kindai University, Sakai, Osaka, 590-0197, Japan.
Tatsuhiko TsunodaLaboratory for Medical Science Mathematics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, 113-0033, Japan. tsunoda@bs.s.u-tokyo.ac.jp.

Funding

Japan Society for the Promotion of Science 24K15175Japan Society for the Promotion of Science 25K02261
6 · The paper itself

Abstract

Adoptive cell therapy (ACT) with tumor-specific CD8

Indexed as

CD8-Positive T-LymphocytesMelanoma, ExperimentalModels, TheoreticalAdoptive TransferAnimalsLymphocytes, Tumor-InfiltratingMiceMice, Inbred C57BLMyeloid CellsAdoptive cell therapyCD8+ T cellsComputational biologyMathematical modelTumor-infiltrating myeloid cellsTumor microenvironment

Identifiers

PMID42062426
PMCPMC13324383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.