ArticleScientific reports2026
A-stream glaucoma shunt versus trabeculectomy: 1-year results on efficacy and safety.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
To compare surgical efficacy and safety of trabeculectomy (TRAB) and a minimally invasive bleb device called A-stream Glaucoma Shunt, that features an intraluminal ripcord for adjustable flow resistance. Retrospective multicenter study. A total of 68 eyes (30 A-stream, 38 TRAB) with at least 12 months of follow-up. Primary open-angle, pigmentary, or pseudoexfoliation glaucoma with uncontrolled IOP despite maximal medical therapy were included. surgical success at 1 year (IOP ≤ 18 mmHg and ≥ 20% reduction from baseline, with or without medication). At 1 year, Complete and qualified success rates were 56.7% and 80.0% for A-stream and 44.7% and 65.8% for TRAB (p > 0.05). Mean IOP decreased from 24.5 ± 5.5 to 11.4 ± 1.8 mmHg in the A-stream group and from 25.7 ± 4.6 to 11.3 ± 3.3 mmHg in the TRAB group. The mean number of glaucoma medications decreased from 3.7 ± 0.8 to 0.4 ± 0.9 (A-stream) and from 3.8 ± 0.5 to 0.6 ± 1.0 (TRAB). Clinically significant hypotony occurred only in TRAB. The A-stream Glaucoma Shunt achieved IOP and medication reduction comparable to trabeculectomy with fewer hypotony-related complications.
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